Anti-GALE抗体[OTI1C4] (ab118033)


  • 产品名称Anti-GALE抗体[OTI1C4]
    参阅全部 GALE 一抗
  • 描述
    小鼠单克隆抗体[OTI1C4] to GALE
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat, Dog, Human, Monkey
  • 免疫原

    Recombinant full length Human GALE produced in HEK293T cells (NP_000394).

  • 阳性对照
    • HEK293T cell lysate transfected with the pCMV6-ENTRY GALE cDNA; HepG2, HeLa, HT29, A549, COS7, Jurkat, MDCK, PC12 and MCF7 cell lysates.
  • 常规说明

    The clone number has been updated from 1C4 to OTI1C4, both clone numbers name the same clone.



Our Abpromise guarantee covers the use of ab118033 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/2000. Predicted molecular weight: 38 kDa.


  • 功能Catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine.
  • 通路Carbohydrate metabolism; galactose metabolism.
  • 疾病相关Defects in GALE are the cause of epimerase-deficiency galactosemia (EDG) [MIM:230350]; also known as galactosemia type 3. Clinical features include early-onset cataracts, liver damage, deafness and mental retardation. There are two clinically distinct forms of EDG. (1) A benign, or 'peripheral' form with no detectable GALE activity in red blood cells and characterized by mild symptoms. Some patients may suffer no symptoms beyond raised levels of galactose-1-phosphate in the blood. (2) A much rarer 'generalized' form with undetectable levels of GALE activity in all tissues and resulting in severe features such as restricted growth and mental development.
  • 序列相似性Belongs to the sugar epimerase family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ95174 antibody
    • FLJ97302 antibody
    • Galactose 4 epimerase UDP antibody
    • Galactowaldenase antibody
    • galE antibody
    • GALE_HUMAN antibody
    • OTTHUMP00000002991 antibody
    • OTTHUMP00000002994 antibody
    • OTTHUMP00000037931 antibody
    • OTTHUMP00000044857 antibody
    • SDR1E1 antibody
    • short chain dehydrogenase/reductase family 1E member 1 antibody
    • UDP galactose 4 epimerase antibody
    • UDP galactose 4' epimerase antibody
    • UDP glucose 4 epimerase antibody
    • UDP-galactose 4-epimerase antibody
    • UDP-glucose 4-epimerase antibody
    see all

Anti-GALE antibody [OTI1C4] 图像

  • All lanes : Anti-GALE antibody [OTI1C4] (ab118033) at 1/500 dilution

    Lane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNA
    Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY GALE cDNA

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 38 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC201561)
  • All lanes : Anti-GALE antibody [OTI1C4] (ab118033) at 1/500 dilution

    Lane 1 : HepG2 cell lysate
    Lane 2 : HeLa cell lysate
    Lane 3 : HT29 cell lysate
    Lane 4 : A549 cell lysate
    Lane 5 : COS7 cell lysate
    Lane 6 : Jurkat cell lysate
    Lane 7 : MDCK cell lysate
    Lane 8 : PC12 cell lysate
    Lane 9 : MCF7 cell lysate

    Lysates/proteins at 35 µg per lane.

    Predicted band size : 38 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC201561)

Anti-GALE antibody [OTI1C4] (ab118033)参考文献

ab118033 has not yet been referenced specifically in any publications.

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