Anti-Galactosidase alpha抗体(ab28962)

概述

性能

应用

Our Abpromise guarantee covers the use of ab28962 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000 - 1/5000.
WB 1/1000 - 1/5000. Detects a band of approximately 49 kDa (predicted molecular weight: 49 kDa).

靶标

  • 疾病相关Defects in GLA are the cause of Fabry disease (FD) [MIM:301500]. FD is a rare X-linked sphingolipidosis disease where glycolipid accumulates in many tissues. The disease consists of an inborn error of glycosphingolipid catabolism. FD patients show systemic accumulation of globotriaoslyceramide (Gb3) and related glycosphingolipids in the plasma and cellular lysosomes throughout the body. Clinical recognition in males results from characteristic skin lesions (angiokeratomas) over the lower trunk. Patients may show ocular deposits, febrile episodes, and burning pain in the extremities. Death results from renal failure, cardiac or cerebral complications of hypertension or other vascular disease. Heterozygous females may exhibit the disorder in an attenuated form, they are more likely to show corneal opacities.
  • 序列相似性Belongs to the glycosyl hydrolase 27 family.
  • 细胞定位Lysosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AGAL_HUMAN antibody
    • Agalsidase alfa antibody
    • Alpha D galactosidase A antibody
    • Alpha D galactoside galactohydrolase 1 antibody
    • Alpha D galactoside galactohydrolase antibody
    • Alpha gal A antibody
    • Alpha galactosidase A antibody
    • Alpha-D-galactosidase A antibody
    • Alpha-D-galactoside galactohydrolase antibody
    • Alpha-galactosidase A antibody
    • GALA antibody
    • Galactosidase, alpha antibody
    • GLA antibody
    • GLA protein antibody
    • Melibiase antibody
    see all

Anti-Galactosidase alpha antibody (ab28962)参考文献

ab28962 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. It turns out the antibody was made with a multiple antigenic peptide (MAP) and there was no carrier protein involved. Thus there should be no reactivity with BSA. I hope this information helps. Please do not hesitate ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"