Anti-GAL4抗体[5C8] (ab16157)

概述

  • 产品名称
    Anti-GAL4抗体[5C8]
    参阅全部 GAL4 一抗
  • 描述
    小鼠单克隆抗体[5C8] to GAL4
  • 经测试应用
    适用于: WB, IPmore details
  • 种属反应性
    与反应: Saccharomyces cerevisiae
  • 免疫原

    Full length protein corresponding to Saccharomyces cerevisiae GAL4.

  • 表位
    ab16157 recognizes GAL4 derivatives containing the C-terminal activation domain.

应用

Our Abpromise guarantee covers the use of ab16157 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution.
IP Use at an assay dependent dilution.

靶标

  • 相关性
    Function: This protein is a positive regulator for the gene expression of the galactose-induced genes such as GAL1, GAL2, GAL7, GAL10, and MEL1 which encode for the enzymes used to convert galactose to glucose. It recognizes a 17 base pair sequence in (5'-CGGRNNRCYNYNCNCCG-3') the upstream activating sequence (UAS-G) of these genes. Subunit structure: Binds DNA as a homodimer. Interacts directly with the mediator subunits GAL11/MED15 and SRB4/MED17. Domain: The 9aaTAD motif (residues 862 to 870) is a transactivation domain present in a large number of yeast and animal transcription factors. Post-translational modification: Association between GAL11 and GAL4 may serve to expedite phosphorylation of GAL4.
  • 细胞定位
    Nuclear
  • 数据库链接
    • 别名
      • Gal4p antibody
      • GAL81 antibody
      • Regulatory protein GAL4 antibody

    文献

    ab16157 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    Thank you for your enquiyr. This particular antibody reacts with the DNA activation region of the GAL-4 protein.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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