Anti-GAK protein抗体(ab86397)

概述

  • 产品名称Anti-GAK protein抗体
  • 描述
    兔多克隆抗体to GAK protein
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to Human GAK aa 15-45 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: Q6P490

  • 阳性对照
    • Mouse heart tissue lysate. Human hepatocarcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab86397 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 62 kDa.
ELISA 1/1000.
IHC-P 1/50 - 1/100.

靶标

  • 相关性GAK, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5. It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK localizes to the perinuclear area and to the trans-Golgi network. It is also observed on the plasma membrane, probably at focals adhesions. Expression is ubiquitous, wiht highest levels in testis. The protein contains 1 J domain and 1 tensin domain. (Information taken form the supplier datasheet for ab86397)
  • 数据库链接

Anti-GAK protein antibody 图像

  • Anti-GAK protein antibody (ab86397) at 1/100 dilution + mouse heart tissue lysate at 12.5 µg

    Predicted band size : 62 kDa
    Observed band size : 62 kDa
    Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.
  • ab86397 at a 1/1000 dilution staining GAK in hepatocarcinoma tissue. DAB staining.

Anti-GAK protein antibody (ab86397)参考文献

ab86397 has not yet been referenced specifically in any publications.

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