概述

  • 产品名称Anti-GADD45GIP1抗体
    参阅全部 GADD45GIP1 一抗
  • 描述
    小鼠多克隆抗体to GADD45GIP1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-222 of Human GADD45GIP1 (NP_443082).

  • 阳性对照
    • A431 lysate, transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab88769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa.

靶标

  • 功能Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
  • 组织特异性Widely expressed. Highly expressed in the thyroid gland, heart, lymph nodes, trachea and adrenal tissues. Expressed at lower level in liver skeletal muscle, kidney, pancreas, testis, ovary and stomach. Barely detectable in adrenal adenoma and papillary thyroid cancer.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 39S ribosomal protein L59 mitochondrial antibody
    • CKBBP2 antibody
    • CKbetaBP2 antibody
    • CKII beta associating protein antibody
    • CKII beta binding protein 2 antibody
    • CKII beta-associating protein antibody
    • CR6 interacting factor 1 antibody
    • CR6-interacting factor 1 antibody
    • CRIF1 antibody
    • G45IP_HUMAN antibody
    • Gadd45gip1 antibody
    • Growth arrest and DNA damage inducible GADD45G interacting protein antibody
    • growth arrest and DNA damage inducible, gamma interacting protein 1 antibody
    • Growth arrest and DNA damage-inducible proteins-interacting protein 1 antibody
    • MGC4667 antibody
    • MGC4758 antibody
    • MRP L59 antibody
    • p53 responsive gene 6 antibody
    • p53 responsive gene 6 protein antibody
    • p53-responsive gene 6 protein antibody
    • Papillomavirus L2 interacting nuclear protein 1 antibody
    • Papillomavirus L2-interacting nuclear protein 1 antibody
    • PLINP 1 antibody
    • PLINP antibody
    • PLINP-1 antibody
    • PLINP1 antibody
    • PRG6 antibody
    see all

Anti-GADD45GIP1 antibody 图像

  • Anti-GADD45GIP1 antibody (ab88769) at 1 µg + A431 cell lysate at 50 µg

    Predicted band size : 25 kDa
    Observed band size : 25 kDa
  • All lanes : Anti-GADD45GIP1 antibody (ab88769) at 1 µg/ml

    Lane 1 : transfected 293T lysate
    Lane 2 : non transfected 293T lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 25 kDa
    Observed band size : 23 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 27 kDa. We are unsure as to the identity of these extra bands.

Anti-GADD45GIP1 antibody (ab88769)参考文献

ab88769 has not yet been referenced specifically in any publications.

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