Anti-GAD65抗体- Neuronal Marker (ab2348)

概述

  • 产品名称Anti-GAD65抗体- Neuronal Marker
    参阅全部 GAD65 一抗
  • 描述
    兔多克隆抗体to GAD65 - Neuronal Marker
  • 特异性This antibody reacts with a 65 kD protein, known as GAD (Glutamate Decarboxylase)
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    Synthetic peptide (Human).

  • 阳性对照
    • Pancreas
  • 常规说明


    Two forms of GAD exist in adults, GAD 65 and GAD 67, which are encoded by different genes. GAD 65 and GAD 67 are expressed in most GABA containing neurons. GAD 65 appears to be targeted to the membrane and nerve ending, where as GAD 67 is more widely distributed throughout the cell.

性能

应用

Our Abpromise guarantee covers the use of ab2348 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/25 - 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

靶标

  • 功能Catalyzes the production of GABA.
  • 序列相似性Belongs to the group II decarboxylase family.
  • 翻译后修饰Phosphorylated; which does not affect kinetic parameters or subcellular location.
    Palmitoylated; which is required for presynaptic clustering.
  • 细胞定位Cytoplasm > cytosol. Cytoplasmic vesicle. Cell junction > synapse > presynaptic cell membrane. Golgi apparatus membrane. Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 65 kDa glutamic acid decarboxylase antibody
    • DCE 2 antibody
    • DCE2 antibody
    • DCE2_HUMAN antibody
    • GAD 2 antibody
    • GAD 65 antibody
    • GAD-2 antibody
    • GAD-65 antibody
    • Gad2 antibody
    • Glutamate decarboxylase 2 (pancreas) antibody
    • Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa) antibody
    • Glutamate decarboxylase 2 antibody
    • Glutamate Decarboxylase 65 antibody
    • Glutamate decarboxylase 65 kDa isoform antibody
    • Glutamic Acid Decarboxylase 2 antibody
    • Glutamic Acid Decarboxylase 65 antibody
    • MGC161605 antibody
    • MGC161607 antibody
    see all

Anti-GAD65 antibody - Neuronal Marker 图像

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human pancreas tissue, staining GAD65 with ab2348.

Anti-GAD65 antibody - Neuronal Marker (ab2348)参考文献

ab2348 has not yet been referenced specifically in any publications.

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