概述

  • 产品名称Anti-GABARAP抗体
    参阅全部 GABARAP 一抗
  • 描述
    兔多克隆抗体to GABARAP
  • 特异性This antibody recognizes human GABARAP (14 kD).
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide:

    RSEGEKIRKKYPDRVPV

    , corresponding to amino acids 15-31 of Human GABARAP.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab1398 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明Western Blot: use at 1:500-1:1,000 dilution.
    ELISA: use at 1:1,000-1:5,000 dilution
  • 靶标

    • 功能Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
    • 组织特异性Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.
    • 序列相似性Belongs to the ATG8 family.
    • 翻译后修饰The precursor molecule is cleaved by ATG4B to form the cytosolic form, GABARAP-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, GABARAP-II.
    • 细胞定位Endomembrane system. Cytoplasm, cytoskeleton. Golgi apparatus membrane. Cytoplasmic vesicle, autophagosome. Largely associated with intracellular membrane structures including the Golgi apparatus and postsynaptic cisternae. Colocalizes with microtubules (By similarity). Localizes also to discrete punctae along the ciliary axoneme (By similarity).
    • Information by UniProt
    • 数据库链接
    • 别名
      • ATG8A antibody
      • FLC 3B antibody
      • FLC3B antibody
      • FLJ25768 antibody
      • GABA(A) receptor associated protein antibody
      • GABA(A) receptor-associated protein antibody
      • GABARAP a antibody
      • GABARAP antibody
      • Gamma aminobutyric acid receptor associated protein antibody
      • Gamma-aminobutyric acid receptor-associated protein antibody
      • GBRAP_HUMAN antibody
      • MGC120154 antibody
      • MGC120155 antibody
      • MM 46 antibody
      • MM46 antibody
      see all

    Anti-GABARAP antibody (ab1398)参考文献

    This product has been referenced in:
    • Belichenko PV  et al. Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome. J Comp Neurol 512:453-66 (2009). Mouse . Read more (PubMed: 19034952) »

    See 1 Publication for this product

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    DISCOUNT CODE: XXXXXXXXXX
    Expiration date: 03-04-2012
    Value: £227

    I am very pleased to hear you would like to accept our offer and test ab1398 in Drosophila. This code will give you £227 off your next order before the expir...

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    Thank you very much for your interest in our antibodies.

    According to a quick blast check the immunogen of ab1398 has a homology with Drosophila melanogaster of 82%. We generally expect cross reaction of an antibody from 85% homology and mor...

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    Thank you for your enquiry. The immunogen sequence used corresponds to: amino acids 15-31 (RSEGEKIRKKYPDRVPV) of the GABARAP protein. the data sheet has been updated to reflect this information. If you need any further help please do not hesitate to ge...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"