概述

  • 产品名称Anti-GABA抗体
    参阅全部 GABA 一抗
  • 描述
    鸡多克隆抗体to GABA
  • 特异性Fixed tissue cross-reactivity tested with known targets at recommended dilution. No measurable glutaraldehyde-fixed tissue cross-reactivity (<1:1000) against: L-alanine, D/L-aspartate, agmatine, D/L-arginine, L-citrulline, L-cysteine, D/L-glutamate, D/L-glutamine, glutathione, glycine, L-histidine, L-isoleucine, L-lysine, L-leucine, L-methionine, L-asparagine, L-ornithine, L-proline, L-serine, taurine, L-threonine, L-valine, L-tryptophan, L-tyrosine. No measurable reactivity against formaldehyde fixed proteins
  • 经测试应用适用于: ICCmore details
  • 种属反应性
    Not applicable.
  • 免疫原

    4-aminobutyrate cross-linked to purifed fraction V bovine serum albumin with glutaraldehyde.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.05% Thimerosal (merthiolate)
    Constituents: 100mM PBS
  • Concentration information loading...
  • 纯度IgY fraction
  • 纯化说明IgYs were separated from other yolk proteins by serial PEG6000 extractions using a modification of the method of Polsonet al Immunological Investigations.
  • 克隆多克隆
  • 同种型IgY
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab62669 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC
  • 应用说明Endogenous content mapping by LM and EM ICC: 1/100. True dilution at user dilution: 1/32000. Optimal fixation: 0.1-2.5% glutaraldehyde,1% formaldehyde using HPI (High Performance Immunocytochemistry).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABA acts at inhibitory synapses in the brain and spinal cord. Inhibition is provoked by GABA binding resulting in hyperpolarization of the synaptic transmembrane potential of the affected neuron. GABA binding causes ion channels to open allowing either the flow of chloride or potassium ions into or out of the cell.
    • 细胞定位Cell Membrane, Cytoplasmic, Plasma membrane and Secreted
    • 别名
      • 4 aminobutanoic acid antibody
      • GABA antibody
      • Gamma amino butyric acid antibody
      • Gamma aminobutyric acid antibody

    Anti-GABA antibody (ab62669)参考文献

    ab62669 has not yet been referenced specifically in any publications.

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