Anti-GABA A receptor pi抗体(ab116109)

概述

  • 产品名称Anti-GABA A receptor pi抗体
    参阅全部 GABA A receptor pi 一抗
  • 描述
    兔多克隆抗体to GABA A receptor pi
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 40-89 (GFENLTAGYN KFLRPNFGGD PVRIALTLDI ASISSISESN MDYTATIYLR) of Mouse GABA A receptor pi (NP_666129).

  • 阳性对照
    • Mouse Kidney lysate.

性能

应用

Our Abpromise guarantee covers the use of ab116109 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 50 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.
  • 组织特异性Most abundant in the uterus, also expressed in lung, thymus and prostate.
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRP sub-subfamily.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GABA(A) receptor subunit pi antibody
    • GABRP antibody
    • Gamma aminobutyric acid (GABA) A receptor pi antibody
    • Gamma aminobutyric acid A receptor pi antibody
    • Gamma aminobutyric acid receptor pi subunit antibody
    • Gamma aminobutyric acid receptor subunit pi antibody
    • Gamma-aminobutyric acid receptor subunit pi antibody
    • GBRP_HUMAN antibody
    • MGC126386 antibody
    • MGC126387 antibody
    see all

Anti-GABA A receptor pi antibody 图像

  • Anti-GABA A receptor pi antibody (ab116109) at 1 µg/ml + Mouse Kidney Lysate at 10 µg

    Predicted band size : 50 kDa

Anti-GABA A receptor pi antibody (ab116109)参考文献

ab116109 has not yet been referenced specifically in any publications.

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