概述

  • 产品名称Anti-GABA A Receptor beta 3抗体
    参阅全部 GABA A Receptor beta 3 一抗
  • 描述
    兔多克隆抗体to GABA A Receptor beta 3
  • 经测试应用适用于: ELISA, Flow Cyt, WB, IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from the N terminal domain of human GABA A Receptor beta 3.

性能

应用

Our Abpromise guarantee covers the use of ab66430 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration. PubMed: 22563490
Flow Cyt Use at an assay dependent concentration. PubMed: 22563490ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
WB 1/500 - 1/5000. Predicted molecular weight: 54 kDa.
IHC-P Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

靶标

  • 功能Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
  • 疾病相关Epilepsy, childhood absence 5
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB3 sub-subfamily.
  • 细胞定位Cell junction, synapse, postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ECA5 antibody
    • GABA alpha receptor beta-2 subunit antibody
    • GABA(A) receptor subunit beta-3 antibody
    • GABAA receptor beta 3 subunit antibody
    • GABAA receptor subunit beta 3 antibody
    • GABR B3 antibody
    • Gabrb3 antibody
    • Gamma aminobutyric acid (GABA) A receptor beta 3 antibody
    • Gamma aminobutyric acid receptor subunit beta 3 antibody
    • Gamma-aminobutyric acid receptor subunit beta-3 antibody
    • GBRB3_HUMAN antibody
    • MGC9051 antibody
    see all

Anti-GABA A Receptor beta 3 antibody (ab66430)参考文献

This product has been referenced in:
  • Desrues L  et al. Down-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticity. PLoS One 7:e36319 (2012). ELISA, Flow Cyt ; Human . Read more (PubMed: 22563490) »

See 1 Publication for this product

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