Anti-GABA A Receptor alpha 6抗体(ab92747)
Key features and details
- Rabbit polyclonal to GABA A Receptor alpha 6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-GABA A Receptor alpha 6抗体
参阅全部 GABA A Receptor alpha 6 一抗 -
描述
兔多克隆抗体to GABA A Receptor alpha 6 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic peptide corresponding to an internal region of Human GABA A Receptor alpha 6.
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阳性对照
- HeLa or Jurkat cell extracts
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab92747于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Predicted molecular weight: 51 kDa.
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说明 |
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WB
1/500 - 1/1000. Predicted molecular weight: 51 kDa. |
靶标
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功能
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. -
序列相似性
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA6 sub-subfamily. -
细胞定位
Cell junction > synapse > postsynaptic cell membrane. Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 2559 Human
- Entrez Gene: 14399 Mouse
- Entrez Gene: 29708 Rat
- Omim: 137143 Human
- SwissProt: Q16445 Human
- SwissProt: P16305 Mouse
- SwissProt: P30191 Rat
- Unigene: 90791 Human
see all -
别名
- GABA A antibody
- GABA A Receptor alpha 6 polypeptide antibody
- GABA A receptor alpha 6 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab92747 被引用在 2 文献中.
- Dasdelen MF et al. A Novel Theanine Complex, Mg-L-Theanine Improves Sleep Quality via Regulating Brain Electrochemical Activity. Front Nutr 9:874254 (2022). PubMed: 35449538
- Fan PC et al. The a6 subunit-containing GABAA receptor: A novel drug target for inhibition of trigeminal activation. Neuropharmacology 140:1-13 (2018). PubMed: 30016665