Anti-GABA A Receptor alpha 4抗体(ab4120)

概述

  • 产品名称Anti-GABA A Receptor alpha 4抗体
    参阅全部 GABA A Receptor alpha 4 一抗
  • 描述
    兔多克隆抗体to GABA A Receptor alpha 4
  • 经测试应用适用于: IHC-P, WB, IPmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    Fusion protein of MBP with the amino acid sequence representing the cytosolic loop of the rat GABA-A receptor alpha 4 subunit.

性能

应用

Our Abpromise guarantee covers the use of ab4120 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration. PubMed: 18539546
WB 1/1000. Predicted molecular weight: 66 kDa.
IP Use at an assay dependent concentration.

靶标

  • 功能GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA4 sub-subfamily.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GABA(A) receptor subunit alpha 4 antibody
    • GABA(A) receptor subunit alpha-4 antibody
    • GABR A4 antibody
    • GABRA 4 antibody
    • Gabra4 antibody
    • Gamma aminobutyric acid (GABA) A receptor alpha 4 antibody
    • Gamma aminobutyric acid A receptor alpha 4 antibody
    • Gamma aminobutyric acid receptor alpha 4 subunit antibody
    • Gamma aminobutyric acid receptor subunit alpha 4 antibody
    • Gamma-aminobutyric acid receptor subunit alpha-4 antibody
    • GBRA4_HUMAN antibody
    see all

Anti-GABA A Receptor alpha 4 antibody 图像

Anti-GABA A Receptor alpha 4 antibody (ab4120)参考文献

This product has been referenced in:
  • Zhang W  et al. Effect of "jian-pi-zhi-dong decoction" on gamma-aminobutyric Acid in a mouse model of tourette syndrome. Evid Based Complement Alternat Med 2014:407509 (2014). IHC-P ; Mouse . Read more (PubMed: 24812567) »
  • Quadrato G  et al. Modulation of GABAA Receptor Signaling Increases Neurogenesis and Suppresses Anxiety through NFATc4. J Neurosci 34:8630-45 (2014). Read more (PubMed: 24948817) »

See all 4 Publications for this product

Product Wall

Thank you for your enquiry. For a negative control in IP, possible suggestions are using another polyclonal from the same species (in this case a non-relevant rabbit polyclonal), or non-immune rabbit serum. If you have any additional questions, please ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"