Anti-GABA A Receptor alpha 4抗体(ab117080)

概述

  • 产品名称Anti-GABA A Receptor alpha 4抗体
    参阅全部 GABA A Receptor alpha 4 一抗
  • 描述
    山羊多克隆抗体to GABA A Receptor alpha 4
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    C-EKAKRKTSKPPQE

    (with a Cysteine residue linker), corresponding to internal sequence amino acids 349-361 of Human GABA A Receptor alpha 4 (NP_000800.2).

  • 阳性对照
    • Human Frontal Cortex lysate and Human Brain, Cortex tissue

性能

应用

Our Abpromise guarantee covers the use of ab117080 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 62 kDa.
ELISA 1/16000.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA4 sub-subfamily.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GABA(A) receptor subunit alpha 4 antibody
    • GABA(A) receptor subunit alpha-4 antibody
    • GABR A4 antibody
    • GABRA 4 antibody
    • Gabra4 antibody
    • Gamma aminobutyric acid (GABA) A receptor alpha 4 antibody
    • Gamma aminobutyric acid A receptor alpha 4 antibody
    • Gamma aminobutyric acid receptor alpha 4 subunit antibody
    • Gamma aminobutyric acid receptor subunit alpha 4 antibody
    • Gamma-aminobutyric acid receptor subunit alpha-4 antibody
    • GBRA4_HUMAN antibody
    see all

Anti-GABA A Receptor alpha 4 antibody 图像

  • Anti-GABA A Receptor alpha 4 antibody (ab117080) at 0.1 µg/ml + Human Frontal Cortex lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 62 kDa
  • Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with ab117080 followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-GABA A Receptor alpha 4 antibody (ab117080)参考文献

ab117080 has not yet been referenced specifically in any publications.

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