Anti-GABA A Receptor alpha 3抗体(ab72446)


  • 产品名称
    Anti-GABA A Receptor alpha 3抗体
    参阅全部 GABA A Receptor alpha 3 一抗
  • 描述
    兔多克隆抗体to GABA A Receptor alpha 3
  • 经测试应用
    适用于: WB, IHC-Frmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    Fusion protein from N-terminal region of rat GABA A Receptor alpha 3

  • 阳性对照
    • rat brain lysates


  • 形式
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 50% Glycerol, 0.1mg/ml BSA, 150mM Sodium chloride, 10mM HEPES, pH 7.5
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
  • 同种型
  • 研究领域


Our Abpromise guarantee covers the use of ab72446 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Detects a band of approximately 55 kDa (predicted molecular weight: 55 kDa).
IHC-Fr 1/100.


  • 功能
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • 序列相似性
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA3 sub-subfamily.
  • 细胞定位
    Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GABA A Receptor alpha 3 antibody
    • GABA(A) receptor subunit alpha 3 antibody
    • GABA(A) receptor subunit alpha-3 antibody
    • GABR A3 antibody
    • GABRA 3 antibody
    • Gabra3 antibody
    • Gamma aminobutyric acid (GABA) A receptor alpha 3 antibody
    • Gamma aminobutyric acid A receptor alpha 3 antibody
    • Gamma aminobutyric acid receptor subunit alpha 3 antibody
    • Gamma-aminobutyric acid receptor subunit alpha-3 antibody
    • GBRA3_HUMAN antibody
    • MGC33793 antibody
    see all


  • All lanes : Anti-GABA A Receptor alpha 3 antibody (ab72446) at 1/1000 dilution

    Lane 1 : wild type rat brain lysates
    Lane 2 : GABA A Receptor alpha 3 knock out rat brain lysates

    Predicted band size : 55 kDa
    Observed band size : 55 kDa


This product has been referenced in:
  • Kaneko Y  et al. Oxytocin modulates GABAAR subunits to confer neuroprotection in stroke in vitro. Sci Rep 6:35659 (2016). WB ; Rat . Read more (PubMed: 27767042) »
  • Bates RC  et al. Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits. Neuroscience 273:52-64 (2014). Read more (PubMed: 24836856) »

See all 2 Publications for this product


Thank you for your response. I am sorry to hear of this continued difficulty.

The images that you mentioned were not included in this email. Would you be able to re-send those to me?

As always, this product is covered ...

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Thank you for your reply and for sending the information.

The protocol information will be very helpful to us. Please keep me updated about the results using the replacement antibody, and let me know if there is anything else that we can do f...

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Thanks for your call today.

As you requested, I'm sending a vial of ab23703 (Anti-Cannabinoid Receptor I antibody) free of charge on the order ***. This order will ship out tonight and get to you tomorrow.

Would you mindbriefly answe...

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I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has caused. As requested, I have issued a free of charge replacement for one vial of ab72446.

To check the status of the order please contact ou...

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Thanks for re-sending the images.

If you feel the vial of ab72446 is not performing as expected, I would be happy to offer a replacement of any primary antibody, credit or refund. Typically our guarantee extends to 6 months from receipt but i...

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Thank you for your enquiry.

I have been unable to locate the ferret protein sequence for GABA A Receptor alpha 3. If you have it or know where I can find it please let me know. I can then forward this sequence information to the lab for an al...

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Thank you for your reply. The anti-GABA A Receptor alpha 3 antibody, ab72446, is covered under our Abpromise and so is guaranteed to work in IHC-Fr on mouse tissue. If the antibody fails to perform as stated and if the scientific support team cannot he...

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Thank you for contacting Abcam. The lab has gotten back to my request for more information on the IHC protocol that was used to test ab72446. Below is the protocol that they have sent me. I have also attached Abcams general IHC and IHC-Fr protocol guid...

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Thank you for contacting Abcam. The only information I have been able to find about the IHC-Fr protocol use so far is that it was tested at 1/100 against on Rat amygdala (4% PFA + 15% picric acid fixed frozen sections. I am going to email the lab for m...

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