Anti-GABA A Receptor alpha 2抗体(ab72445)

概述

  • 产品名称Anti-GABA A Receptor alpha 2抗体
    参阅全部 GABA A Receptor alpha 2 一抗
  • 描述
    兔多克隆抗体to GABA A Receptor alpha 2
  • 特异性ab72445 is specific for GABA A Receptor alpha 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat
    预测可用于: Cow, Dog, Human, Non Human Primates, Zebrafish
  • 免疫原

    Fusion protein from the cytoplasmic loop of rat GABA A Receptor alpha 2

  • 阳性对照
    • rat brain lysates

性能

应用

Our Abpromise guarantee covers the use of ab72445 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).

靶标

  • 功能GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GABA A receptor subunit alpha 2 antibody
    • GABA antibody
    • GABA(A) receptor subunit alpha 2 antibody
    • GABA(A) receptor subunit alpha-2 antibody
    • GABR A2 antibody
    • GABRA 2 antibody
    • GABRA2 antibody
    • GABRA2 protein antibody
    • Gamma aminobutyric acid (GABA) A receptor alpha 2 antibody
    • Gamma aminobutyric acid A receptor alpha 2 antibody
    • Gamma aminobutyric acid receptor alpha 2 subunit antibody
    • Gamma aminobutyric acid receptor subunit alpha 2 antibody
    • Gamma-aminobutyric acid receptor subunit alpha-2 antibody
    • GBRA2_HUMAN antibody
    see all

Anti-GABA A Receptor alpha 2 antibody 图像

  • All lanes : Anti-GABA A Receptor alpha 2 antibody (ab72445) at 1/1000 dilution

    Lane 1 : Wild type Mouse brain lysates
    Lane 2 : GABA A Receptor alpha 2 knockout mouse brain lysate


    Predicted band size : 51 kDa
    Observed band size : 51 kDa

Anti-GABA A Receptor alpha 2 antibody (ab72445)参考文献

This product has been referenced in:
  • Zhou C  et al. Altered cortical GABAA receptor composition, physiology, and endocytosis in a mouse model of a human genetic absence epilepsy syndrome. J Biol Chem 288:21458-72 (2013). WB . Read more (PubMed: 23744069) »
  • Faroni A  et al. Expression of Functional ?-Aminobutyric Acid Type A Receptors in Schwann-Like Adult Stem Cells. J Mol Neurosci : (2012). WB ; Human . Read more (PubMed: 22215379) »

See all 2 Publications for this product

Product Wall

Thank you for contacting Abcam regarding the immunogen information for ab72445 and ab103707.

Regarding ab103707, the immunogen was generated from a peptide within aa53-83, corresponding to an extracellular domain of the protein. The specific a...

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Thank you for your reply.

There are few protocol variations that may help improve the results that your are getting:

1 - Do not heat/boil your samples. When looking at transmembrane proteins, it is advisable to not heat the sample a...

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Thank you for contacting Abcam.

I would be more than happy to help out in any way that I can. I just have a few more protocol questions for you:

1 - Are you boiling your samples? If so for how long?

2 - What percentage of...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"