功能Probably involved in EGF and insulin receptor signaling.
序列相似性Belongs to the GAB family. Contains 1 PH domain.
翻译后修饰Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.
Detection of GAB1 by Western Blot of Immunprecipitate.
ab117774 at 1µg/ml staining GAB1 in HeLa whole cell lysate immunoprecipitated using ab117774 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 30 seconds.
Anti-GAB1 antibody (ab117774)参考文献
has not yet been referenced specifically in any publications.