Anti-G protein alpha inhibitor 1抗体(ab81447)

概述

  • 产品名称Anti-G protein alpha inhibitor 1抗体
    参阅全部 G protein alpha inhibitor 1 一抗
  • 描述
    兔多克隆抗体to G protein alpha inhibitor 1
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Saccharomyces cerevisiae, Drosophila melanogaster, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 144-193, REYQLNDSAA YYLNDLDRIA QPNYIPTQQD VLRTRVKTTG IVETHFTFKD, of Human G protein alpha inhibitor 1 (NP_002060).

  • 阳性对照
    • Fetal Brain Lysate

性能

应用

Our Abpromise guarantee covers the use of ab81447 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay 1:12500.

WB Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
  • 序列相似性Belongs to the G-alpha family. G(i/o/t/z) subfamily.
  • 细胞定位Nucleus. Cytoplasm. Cell membrane. Cytoplasm > cytoskeleton > centrosome. Localized at the plasma membrane throughout mitosis. Colocalizes with RIC8A and RGS14 at the plasma membrane (By similarity). Localizes in the centrosomes of interphase and mitotic cells, but not in centrosomes during cytokinesis. Detected at the cleavage furrow or the midbody.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Adenylate cyclase inhibiting G alpha protein antibody
    • Adenylate cyclase inhibitory protein antibody
    • Adenylate cyclase-inhibiting G alpha protein antibody
    • G protein alpha inhibiting 1 antibody
    • G protein alpha inhibiting activity polypeptide 1 antibody
    • Gi antibody
    • Gi inhibitory G protein antibody
    • Gi1 protein alpha subunit antibody
    • GNAI 1 antibody
    • GNAI1 antibody
    • GNAI1_HUMAN antibody
    • Guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 1 antibody
    • Guanine nucleotide binding protein alpha inhibiting activity polypeptide 1 antibody
    • Guanine nucleotide binding protein G(i) alpha 1 subunit antibody
    • Guanine nucleotide-binding protein G(i) subunit alpha-1 antibody
    • OTTHUMP00000161319 antibody
    • OTTHUMP00000208047 antibody
    see all

Anti-G protein alpha inhibitor 1 antibody 图像

  • Anti-G protein alpha inhibitor 1 antibody (ab81447) at 1 µg/ml (in 5% skim milk / PBS buffer) + Fetal Brain Lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 40 kDa
    Observed band size : 40 kDa
  • Anti-G protein alpha inhibitor 1 antibody (ab81447) at 1/1000 dilution + Nthy-ori cell lysate at 50 µg

    Secondary
    HRP anti-rabbit at 1/2000 dilution

    Predicted band size : 40 kDa

Anti-G protein alpha inhibitor 1 antibody (ab81447)参考文献

ab81447 has not yet been referenced specifically in any publications.

Product Wall

Merci pour votre émail et votre patience.
Veuillez trouver les offres de test ci-dessous.
Comme convenu, j'ai aussi fait les inquêtes pour le potentiel de crossréaction de certains anticorps contre GNAI1:
-Pour le ab81447 le laboratoire ...

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Merci de votre appel et votre intérêt pour nos anticorps contre la G protein alpha inhibitor 1 et 2.
Comme discuté au téléphone, j'ai contacté maintenant les laboratoires produisants le ab81447 et ab102014 afin d'avoir plus d'information sur la po...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"