Anti-G protein alpha inhibitor 1抗体[2B8-2A5] (ab118434)

概述

  • 产品名称Anti-G protein alpha inhibitor 1抗体[2B8-2A5]
    参阅全部 G protein alpha inhibitor 1 一抗
  • 描述
    小鼠单克隆抗体[2B8-2A5] to G protein alpha inhibitor 1
  • 经测试应用适用于: WB, IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-354 of Human G protein alpha inhibitor 1 with proprietary tag (AAH26326).

  • 阳性对照
    • Human skin and adrenal tissues; Human liver tissue lysate; Recombinant Human G protein alpha inhibitor 1 protein.

性能

应用

Our Abpromise guarantee covers the use of ab118434 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 40 kDa.
IHC-P Use a concentration of 5 µg/ml.
ELISA Use at an assay dependent concentration.

靶标

  • 功能Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
  • 序列相似性Belongs to the G-alpha family. G(i/o/t/z) subfamily.
  • 细胞定位Nucleus. Cytoplasm. Cell membrane. Cytoplasm > cytoskeleton > centrosome. Localized at the plasma membrane throughout mitosis. Colocalizes with RIC8A and RGS14 at the plasma membrane (By similarity). Localizes in the centrosomes of interphase and mitotic cells, but not in centrosomes during cytokinesis. Detected at the cleavage furrow or the midbody.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Adenylate cyclase inhibiting G alpha protein antibody
    • Adenylate cyclase inhibitory protein antibody
    • Adenylate cyclase-inhibiting G alpha protein antibody
    • G protein alpha inhibiting 1 antibody
    • G protein alpha inhibiting activity polypeptide 1 antibody
    • Gi antibody
    • Gi inhibitory G protein antibody
    • Gi1 protein alpha subunit antibody
    • GNAI 1 antibody
    • GNAI1 antibody
    • GNAI1_HUMAN antibody
    • Guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 1 antibody
    • Guanine nucleotide binding protein alpha inhibiting activity polypeptide 1 antibody
    • Guanine nucleotide binding protein G(i) alpha 1 subunit antibody
    • Guanine nucleotide-binding protein G(i) subunit alpha-1 antibody
    • OTTHUMP00000161319 antibody
    • OTTHUMP00000208047 antibody
    see all

Anti-G protein alpha inhibitor 1 antibody [2B8-2A5] 图像

  • ab118434 at 5µg/ml staining G protein alpha inhibitor 1 in Formalin-fixed, Paraffin-embedded Human skin tissue by Immunohistochemistry.
  • ab118434 at 5µg/ml staining G protein alpha inhibitor 1 in Formalin-fixed, Paraffin-embedded Human adrenal tissue by Immunohistochemistry.
  • Anti-G protein alpha inhibitor 1 antibody [2B8-2A5] (ab118434) + Human liver tissue lysate

    Predicted band size : 40 kDa
  • Detection limit for recombinant tagged G protein alpha inhibitor 1 is approximately 1 ng/ml as a capture antibody.

Anti-G protein alpha inhibitor 1 antibody [2B8-2A5] (ab118434)参考文献

ab118434 has not yet been referenced specifically in any publications.

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