Anti-G protein alpha抗体(ab58651)

概述

  • 产品名称Anti-G protein alpha抗体
    参阅全部 G protein alpha 一抗
  • 描述
    兔多克隆抗体to G protein alpha
  • 特异性This antibody reacts with G protein alpha.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • 免疫原

    Synthetic peptide: LFLNKQDLLA EKVLAGKSKI EDYFPEFARY TTPEDATPEP GEDPRVTRAK, corresponding to amino acids 289-338 of Human G protein alpha

  • 阳性对照
    • Jurkat cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab58651 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性GTP-binding proteins (G-proteins)are a family of heterotrimeric proteins that play a critical role in signal transduction by coupling cell surface, 7-transmembrane domain receptors to intracellular signaling pathways including second messenger generation (such as cyclic AMP, calcium and diacylglycerol), protein phosphorylation, ion channel activation, gene induction, cell growth and differentiation. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit.
  • 细胞定位Cell Membrane
  • 数据库链接
  • 别名
    • Adenylate cyclase stimulating G alpha protein antibody
    • AHO antibody
    • C20orf45 antibody
    • Extra large alphas protein antibody
    • GNAS complex locus antibody
    • GNAS1 antibody
    • GPSA antibody
    • GSA antibody
    • GSP antibody
    • Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 antibody
    • Guanine nucleotide binding protein G(s) alpha subunit antibody
    • Guanine nucleotide binding protein G(s) subunit alpha isoforms XLas antibody
    • guanine nucleotide regulatory protein antibody
    • NESP antibody
    • Neuroendocrine secretory protein antibody
    • PHP1A antibody
    • PHP1B antibody
    • PHP1C antibody
    • POH antibody
    • RP4-543J19.4 antibody
    • Secretogranin VI antibody
    • XLalphas antibody
    see all

Anti-G protein alpha antibody 图像

  • Anti-G protein alpha antibody (ab58651) at 2.5 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 42 kDa
    Observed band size : 42 kDa

Anti-G protein alpha antibody (ab58651)参考文献

ab58651 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry and patience. ab58651 and ab58916 are different peptides against GNAS complex. Human Gnas1 and Gnas2 have 100% and 98% homology, respective to antibodies. The homology is very low against other subunits but the cross-reac...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"