Anti-G protein alpha抗体[0.N.305] (ab34027)

概述

  • 产品名称Anti-G protein alpha抗体[0.N.305]
    参阅全部 G protein alpha 一抗
  • 描述
    小鼠单克隆抗体[0.N.305] to G protein alpha
  • 特异性Recognizes Guanine nucleotide-binding protein G(i) subunit alpha-1 (Rat). Does not crossreact with Guanine nucleotide-binding protein G(t) subunit alpha-1 (Gnat1), Guanine nucleotide-binding protein G(o) subunit alpha (Gnao1), Guanine nucleotide-binding protein G(i) subunit alpha-2 (Gnai2), Guanine nucleotide-binding protein G(k) subunit alpha (Gnai3), Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Gnas).
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Guinea pig, Cow, Human
  • 免疫原

    Partially purified G protein alpha protein from rat brain (39-42kD)

  • 阳性对照
    • IMR-5 cells or brain

性能

应用

Our Abpromise guarantee covers the use of ab34027 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 45 kDa.

靶标

  • 相关性GTP-binding proteins (G-proteins)are a family of heterotrimeric proteins that play a critical role in signal transduction by coupling cell surface, 7-transmembrane domain receptors to intracellular signaling pathways including second messenger generation (such as cyclic AMP, calcium and diacylglycerol), protein phosphorylation, ion channel activation, gene induction, cell growth and differentiation. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit.
  • 细胞定位Cell Membrane
  • 数据库链接
  • 别名
    • Adenylate cyclase stimulating G alpha protein antibody
    • AHO antibody
    • C20orf45 antibody
    • Extra large alphas protein antibody
    • GNAS complex locus antibody
    • GNAS1 antibody
    • GPSA antibody
    • GSA antibody
    • GSP antibody
    • Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 antibody
    • Guanine nucleotide binding protein G(s) alpha subunit antibody
    • Guanine nucleotide binding protein G(s) subunit alpha isoforms XLas antibody
    • guanine nucleotide regulatory protein antibody
    • NESP antibody
    • Neuroendocrine secretory protein antibody
    • PHP1A antibody
    • PHP1B antibody
    • PHP1C antibody
    • POH antibody
    • RP4-543J19.4 antibody
    • Secretogranin VI antibody
    • XLalphas antibody
    see all

Anti-G protein alpha antibody [0.N.305] (ab34027)参考文献

ab34027 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry and patience. ab58651 and ab58916 are different peptides against GNAS complex. Human Gnas1 and Gnas2 have 100% and 98% homology, respective to antibodies. The homology is very low against other subunits but the cross-reac...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"