概述

  • 产品名称Anti-FYB抗体
    参阅全部 FYB 一抗
  • 描述
    兔多克隆抗体to FYB
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 382-658 of Human FYB (NP_955367).

  • 阳性对照
    • 293T, Jurkat and Raji whole cell lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab111611 is purified by antigen-affinity chromatography.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111611 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 85 kDa.

靶标

  • 功能Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.
  • 组织特异性Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.
  • 序列相似性Contains 1 SH3 domain.
  • 翻译后修饰T-cell receptor ligation leads to increased tyrosine phosphorylation.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ADAP antibody
    • Adhesion and degranulation promoting adaptor protein antibody
    • FYB 120/130 antibody
    • Fyb antibody
    • FYB-120/130 antibody
    • FYB_HUMAN antibody
    • FYN binding protein antibody
    • FYN T binding protein antibody
    • FYN-binding protein antibody
    • FYN-T-binding protein antibody
    • p120/p130 antibody
    • PRO0823 antibody
    • SLAP 130 antibody
    • SLAP-130 antibody
    • SLAP130 antibody
    • SLP 76 associated phosphoprotein antibody
    • SLP-76-associated phosphoprotein antibody
    • SLP76 associated phosphoprotein antibody
    see all

Anti-FYB antibody 图像

  • Anti-FYB antibody (ab111611) at 1/1000 dilution + Raji whole cell lysate at 30 µg

    Predicted band size : 85 kDa

Anti-FYB antibody (ab111611)参考文献

ab111611 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"