产品名称 Anti-FYB抗体 参阅全部 FYB 一抗
WB more details
Recombinant fragment, corresponding to a region within amino acids 382-658 of Human FYB (NP_955367).
293T, Jurkat and Raji whole cell lysates.
存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
存储溶液 pH: 7.00 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
纯度 Immunogen affinity purified
纯化说明 ab111611 is purified by antigen-affinity chromatography.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 85 kDa.
功能 Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.
组织特异性 Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.
序列相似性 Contains 1 SH3 domain.
翻译后修饰 T-cell receptor ligation leads to increased tyrosine phosphorylation.
细胞定位 Cytoplasm. Nucleus.
Information by UniProt
Adhesion and degranulation promoting adaptor protein antibody
FYB 120/130 antibody
Anti-FYB antibody (ab111611)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"