概述

  • 产品名称Anti-FUSIP1抗体
    参阅全部 FUSIP1 一抗
  • 描述
    兔多克隆抗体to FUSIP1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Chicken, Guinea pig, Cow, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (SRYLRPPNTS LFVRNVADDT RSEDLRREFG RYGPIVDVYV PLDFYTRRPR) of Human FUSIP1 (NP_473357).

  • 阳性对照
    • Human fetal thymus lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab94600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 31 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70. Required for splicing repression in M-phase cells and after heat shock. May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator.
  • 组织特异性Widely expressed.
  • 序列相似性Belongs to the splicing factor SR family.
    Contains 1 RRM (RNA recognition motif) domain.
  • 翻译后修饰Phosphorylated. Fully dephosphorylated in mitosis and partially dephosphorylated on heat shock. Isoform 3 is phosphorylated on Ser-168.
  • 细胞定位Nucleus speckle. Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 40 kDa SR repressor protein antibody
    • 40 kDa SR-repressor protein antibody
    • Anti TLS associated protein with SR repeats antibody
    • arginine/serine-rich 13A antibody
    • FUS interacting protein serine arginine rich 1 antibody
    • FUS interacting protein serine arginine rich 2 antibody
    • FUS interacting serine arginine rich protein 1 antibody
    • FUS-interacting serine-arginine-rich protein 1 antibody
    • FUSIP1 antibody
    • FUSIP2 antibody
    • NSSR antibody
    • OTTHUMP00000015774 antibody
    • Serine arginine repressor protein 40 kDa antibody
    • Serine/arginine-rich splicing factor 10 antibody
    • SFRS13 antibody
    • SFRS13A antibody
    • Splicing factor antibody
    • Splicing factor arginine serine rich 13 antibody
    • Splicing factor SRp38 antibody
    • SRp38 antibody
    • SRp40 antibody
    • SRrp40 antibody
    • SRS10_HUMAN antibody
    • Srsf10 antibody
    • TASR antibody
    • TASR1 antibody
    • TASR2 antibody
    • TLS associated protein TASR1 antibody
    • TLS associated protein TASR2 antibody
    • TLS associated protein with Ser Arg repeats antibody
    • TLS associated protein with SR repeats antibody
    • TLS associated serine arginine protein 1 antibody
    • TLS associated serine arginine protein 2 antibody
    • TLS associated serine arginine protein antibody
    • TLS associated SR protein antibody
    • TLS-associated protein with Ser-Arg repeats antibody
    • TLS-associated protein with SR repeats antibody
    • TLS-associated serine-arginine protein antibody
    • TLS-associated SR protein antibody
    see all

Anti-FUSIP1 antibody 图像

  • Anti-FUSIP1 antibody (ab94600) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal thymus lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 31 kDa

Anti-FUSIP1 antibody (ab94600)参考文献

ab94600 has not yet been referenced specifically in any publications.

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