Anti-Fucose mutarotase抗体(ab122543)

概述

  • 产品名称Anti-Fucose mutarotase抗体
    参阅全部 Fucose mutarotase 一抗
  • 描述
    兔多克隆抗体to Fucose mutarotase
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: MVALKGVPAL LSPELLYALA RMGHGDEIVL ADLNFPASSI CQCGPMEIRA DGLGIPQLLE AVL, corresponding to amino acids 1-63 of Human Fucose mutarotase.

  • 阳性对照
    • Human kidney tissue.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab122543 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Perform heat mediated antigen retrieval at pH6 before commencing with IHC staining protocol.

靶标

  • 功能Involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes.
  • 序列相似性Belongs to the rbsD / fucU family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C10orf125 antibody
    • Chromosome 10 open reading frame 125 antibody
    • FUCM_HUMAN antibody
    • Fucose mutarotase antibody
    • FUCU antibody
    • FUOM antibody
    • Protein fucU homolog antibody
    see all

Anti-Fucose mutarotase antibody 图像

  • ab122543, at 1/125 dilution, staining Fucose mutarotase in paraffin-embedded Human kidney tissue by Immunohistochemistry, showing strong cytoplasmic positivity in cells in tubules.

Anti-Fucose mutarotase antibody (ab122543)参考文献

ab122543 has not yet been referenced specifically in any publications.

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