概述

  • 产品名称Anti-FUCA1抗体
    参阅全部 FUCA1 一抗
  • 描述
    兔多克隆抗体to FUCA1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide, corresponding to a region within internal sequence amino acids 143-192 (TNWPSPVSWN WNSKDVGPHR DLVGELGTAL RKRNIRYGLY HSLLEWFHPL) of Human FUCA1 (NP_000138).

  • 阳性对照
    • HT1080 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab98310 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
  • 疾病相关Defects in FUCA1 are the cause of fucosidosis (FUCA1D) [MIM:230000]. FUCA1D is an autosomal recessive lysosomal storage disease characterized by accumulation of fucose-containing glycolipids and glycoproteins in various tissues. Clinical signs include facial dysmorphism, dysostosis multiplex, moderate hepatomegaly, severe intellectual deficit, deafness, and according to age, angiokeratomas.
  • 序列相似性Belongs to the glycosyl hydrolase 29 family.
  • 细胞定位Lysosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Alpha L fucosidase I antibody
    • Alpha L fucoside fucohydrolase antibody
    • Alpha-L-fucosidase 1 antibody
    • Alpha-L-fucosidase I antibody
    • Alpha-L-fucoside fucohydrolase 1 antibody
    • FUCA antibody
    • FUCA1 antibody
    • FUCO_HUMAN antibody
    • fucosidase, alpha-L, tissue antibody
    • fucosidase, alpha-L- 1, tissue antibody
    • Tissue alpha L fucosidase antibody
    • Tissue alpha-L-fucosidase antibody
    see all

Anti-FUCA1 antibody 图像

  • Anti-FUCA1 antibody (ab98310) at 1 µg/ml + HT1080 cell lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 54 kDa

Anti-FUCA1 antibody (ab98310)参考文献

ab98310 has not yet been referenced specifically in any publications.

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