概述

  • 产品名称Anti-FUCA1抗体
    参阅全部 FUCA1 一抗
  • 描述
    兔多克隆抗体to FUCA1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region of Human FUCA1

  • 阳性对照
    • Fetal liver lysate

性能

应用

Our Abpromise guarantee covers the use of ab76400 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

Titre using peptide based assay, 1:312500.

靶标

  • 功能Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
  • 疾病相关Defects in FUCA1 are the cause of fucosidosis (FUCA1D) [MIM:230000]. FUCA1D is an autosomal recessive lysosomal storage disease characterized by accumulation of fucose-containing glycolipids and glycoproteins in various tissues. Clinical signs include facial dysmorphism, dysostosis multiplex, moderate hepatomegaly, severe intellectual deficit, deafness, and according to age, angiokeratomas.
  • 序列相似性Belongs to the glycosyl hydrolase 29 family.
  • 细胞定位Lysosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Alpha L fucosidase I antibody
    • Alpha L fucoside fucohydrolase antibody
    • Alpha-L-fucosidase 1 antibody
    • Alpha-L-fucosidase I antibody
    • Alpha-L-fucoside fucohydrolase 1 antibody
    • FUCA antibody
    • FUCA1 antibody
    • FUCO_HUMAN antibody
    • fucosidase, alpha-L, tissue antibody
    • fucosidase, alpha-L- 1, tissue antibody
    • Tissue alpha L fucosidase antibody
    • Tissue alpha-L-fucosidase antibody
    see all

Anti-FUCA1 antibody 图像

  • Anti-FUCA1 antibody (ab76400) at 1 µg/ml (in 5% skim milk / PBS buffer) + fetal liver lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 54 kDa
    Observed band size : 54 kDa

Anti-FUCA1 antibody (ab76400)参考文献

ab76400 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab76400.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"