Anti-FTSJD2抗体(ab70388)
Key features and details
- Rabbit polyclonal to FTSJD2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-FTSJD2抗体
参阅全部 FTSJD2 一抗 -
描述
兔多克隆抗体to FTSJD2 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Chimpanzee, Rhesus monkey, Gorilla, Orangutan -
免疫原
Synthetic peptide corresponding to Human FTSJD2 (C terminal).
Database link: Q8N1G2 -
阳性对照
- Whole cell lysate from 293T cells transfected with a myc-FTSJD2 expression construct. Whole cell lysate from 293T cells. Whole cell lysate from G361 cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7
Preservative: 0.09% Sodium azide
Constituents: 1.815% Tris, 1.764% Sodium citrate, 0.021% PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab70388于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/5000 - 1/25000. Detects a band of approximately 100 kDa (predicted molecular weight: 96 kDa).
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说明 |
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WB
1/5000 - 1/25000. Detects a band of approximately 100 kDa (predicted molecular weight: 96 kDa). |
靶标
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功能
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. -
序列相似性
Contains 1 G-patch domain.
Contains 1 RrmJ-type SAM-dependent 2'-O-MTase domain.
Contains 1 WW domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 23070 Human
- Entrez Gene: 100172922 Orangutan
- SwissProt: Q8N1G2 Human
- SwissProt: Q5R981 Orangutan
- Unigene: 520102 Human
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别名
- Cap methyltransferase 1 antibody
- Cap-specific mRNA (nucleoside-2''-O-)-methyltransferase 1 antibody
- Cap1 2''O-ribose methyltransferase 1 antibody
see all
图片
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All lanes : Anti-FTSJD2 antibody (ab70388) at 0.2 µg
Lane 1 : HeLa whole cell lysate
Lane 2 : HEK293T whole cell lysate
Lysates/proteins at 50 µg per lane.
Predicted band size: 96 kDa -
All lanes : Anti-FTSJD2 antibody (ab70388) at 0.1 µg/ml
Lane 1 : Whole cell lysate from 293T cells transfected with a
myc-FTSJD2 expression construct at 15 µg
Lane 2 : Whole cell lysate from 293T cells that were
mock transfected at 60 µg
Lane 3 : Whole cell lysate from G361 cells at 15 µg
Predicted band size: 96 kDa
Observed band size: 100 kDa why is the actual band size different from the predicted?
Additional bands at: 50 kDa, 60 kDa. We are unsure as to the identity of these extra bands.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab70388 尚未被引用在任何文献中。