存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
存储溶液 Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris saline, pH 7.3
Concentration information loading...
纯度 Immunogen affinity purified
纯化说明 Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 56 kDa.
功能 May be involved in microtubule organization and stabilization.
组织特异性 Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord.
序列相似性 Contains 1 B30.2/SPRY domain. Contains 1 COS domain. Contains 1 fibronectin type-III domain.
结构域 B30.2 box contains a microtubule-binding site.
细胞定位 Cytoplasm > cytoskeleton > centrosome. Nucleus. Cytoplasm. Cleavage furrow. Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.
Information by UniProt
Fibronectin type 3 and SPRY (spla, ryanodine) domain containing (with coiled-coil motif) 1 antibody
Fibronectin type 3 and SPRY domain containing 1 antibody
Fibronectin type III and SPRY domain containing 1 antibody
Anti-FSD1 antibody (ab42691)参考文献
has not yet been referenced specifically in any publications.
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