概述

  • 产品名称Anti-FRMD4B抗体
  • 描述
    兔多克隆抗体to FRMD4B
  • 经测试应用适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence, corresponding to amino acids 899-1009 of Human FRMD4B.

  • 阳性对照
    • Human cerebellum tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab121310 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

靶标

  • 功能Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein.
  • 序列相似性Contains 1 FERM domain.
  • 细胞定位Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 6030440G05Rik antibody
    • FERM domain-containing protein 4B antibody
    • FRM4B_HUMAN antibody
    • Frmd4b antibody
    • GRP1-binding protein GRSP1 antibody
    • GRSP1 antibody
    see all

Anti-FRMD4B antibody 图像

  • Immunofluorescent staining of Human cell line U-251MG shows positivity in golgi apparatus and centrosome. Recommended concentration of ab121310 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab121310 at 1/200 dilution staining FRMD4B in Paraffin-embedded Human cerebellum tissue by Immunohistochemistry.

Anti-FRMD4B antibody (ab121310)参考文献

ab121310 has not yet been referenced specifically in any publications.

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