概述

  • 产品名称Anti-FRK抗体
    参阅全部 FRK 一抗
  • 描述
    兔多克隆抗体to FRK
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 36-85 (CSPQSQRHGH YFVALFDYQA RTAEDLSFRA GDKLQVLDTL HEGWWFARHL) of Human FRK (NP_002022).

  • 阳性对照
    • Transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab87201 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
  • 组织特异性Restricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin.
  • 序列相似性Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Beta cell Src homology tyrosine kinase antibody
    • BSK antibody
    • BSK/IYK antibody
    • C85044 antibody
    • Frk antibody
    • Frk fyn related kinase antibody
    • FRK_HUMAN antibody
    • FYN related kinase antibody
    • FYN-related kinase antibody
    • GASK antibody
    • Gastrointestinal associated kinase antibody
    • Gastrointestinal associated tyrosine kinase antibody
    • GTK antibody
    • GTK, mouse, homolog of antibody
    • Intestine tyrosine kinase antibody
    • Nuclear tyrosine protein kinase RAK antibody
    • Protein-tyrosine kinase 5 antibody
    • PTK5 antibody
    • PTK5 protein tyrosine kinase 5 antibody
    • RAK antibody
    • Tyrosine protein kinase FRK antibody
    • Tyrosine-protein kinase FRK antibody
    see all

Anti-FRK antibody 图像

  • Anti-FRK antibody (ab87201) at 1 µg/ml (in 5% skim milk / PBS buffer) + Transfected 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 58 kDa
    Observed band size : 58 kDa

Anti-FRK antibody (ab87201)参考文献

ab87201 has not yet been referenced specifically in any publications.

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