概述

  • 产品名称
    Anti-FRK抗体[4E1]
    参阅全部 FRK 一抗
  • 描述
    小鼠单克隆抗体[4E1] to FRK
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Purified recombinant fragment of Human FRK expressed in E. Coli.

  • 阳性对照
    • K562 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab91623 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/2000. Predicted molecular weight: 58 kDa.
ELISA 1/10000.

靶标

  • 功能
    Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
  • 组织特异性
    Restricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin.
  • 序列相似性
    Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Beta cell Src homology tyrosine kinase antibody
    • BSK antibody
    • BSK/IYK antibody
    • C85044 antibody
    • Frk antibody
    • Frk fyn related kinase antibody
    • FRK_HUMAN antibody
    • FYN related kinase antibody
    • FYN-related kinase antibody
    • GASK antibody
    • Gastrointestinal associated kinase antibody
    • Gastrointestinal associated tyrosine kinase antibody
    • GTK antibody
    • GTK, mouse, homolog of antibody
    • Intestine tyrosine kinase antibody
    • Nuclear tyrosine protein kinase RAK antibody
    • Protein-tyrosine kinase 5 antibody
    • PTK5 antibody
    • PTK5 protein tyrosine kinase 5 antibody
    • RAK antibody
    • Tyrosine protein kinase FRK antibody
    • Tyrosine-protein kinase FRK antibody
    see all

Anti-FRK antibody [4E1] 图像

  • Anti-FRK antibody [4E1] (ab91623) at 1/500 dilution + K562 cell lysate

    Predicted band size : 58 kDa

实验方案

Anti-FRK antibody [4E1] (ab91623)参考文献

This product has been referenced in:
  • de Wispelaere M  et al. The small molecules AZD0530 and dasatinib inhibit dengue virus RNA replication via Fyn kinase. J Virol 87:7367-81 (2013). Read more (PubMed: 23616652) »

See 1 Publication for this product

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