概述

  • 产品名称Anti-Frequenin抗体
    参阅全部 Frequenin 一抗
  • 描述
    兔多克隆抗体to Frequenin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Cow, Zebrafish
  • 免疫原

    Recombinant protein fragment corresponding to a region within amino acids 1-148 of Human Frequenin (NP_055101)

  • 阳性对照
    • A431 and HepG2 whole cell lysates

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab97754 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/1000. Predicted molecular weight: 22 kDa.

靶标

  • 功能Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.
  • 序列相似性Belongs to the recoverin family.
    Contains 4 EF-hand domains.
  • 细胞定位Golgi apparatus > Golgi stack membrane. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cytoplasm > perinuclear region. Cell membrane. Associated with Golgi stacks. Post-synaptic densities of dendrites, and in the pre-synaptic nerve terminal at neuromuscular junctions.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Flup antibody
    • Freq antibody
    • frequenin (Drosophila) homolog antibody
    • Frequenin homolog antibody
    • Frequenin-like protein antibody
    • Frequenin-like ubiquitous protein antibody
    • NCS-1 antibody
    • ncs1 antibody
    • NCS1_HUMAN antibody
    • Neuronal calcium sensor 1 antibody
    see all

Anti-Frequenin antibody 图像

  • All lanes : Anti-Frequenin antibody (ab97754) at 1/200 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : HepG2 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 22 kDa

Anti-Frequenin antibody (ab97754)参考文献

ab97754 has not yet been referenced specifically in any publications.

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