概述

  • 产品名称Anti-FOXP3抗体
    参阅全部 FOXP3 一抗
  • 描述
    兔多克隆抗体to FOXP3
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Mouse, Human
  • 免疫原

    Three synthetic peptides derived from human FOXP3, conjugated to KLH.

  • 阳性对照
    • An anti thio tested on an induced culture of E. coli.

性能

应用

Our Abpromise guarantee covers the use of ab86006 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明Direct ELISA: 1/40000.
    WB: 1/1000. Predicted molecular weight: 47 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Probable transcription factor. Plays a critical role in the control of immune response.
    • 疾病相关Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.
    • 序列相似性Contains 1 C2H2-type zinc finger.
      Contains 1 fork-head DNA-binding domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AIID antibody
      • DIETER antibody
      • Forkhead box P3 antibody
      • Forkhead box protein P3 antibody
      • FOXP3 antibody
      • FOXP3_HUMAN antibody
      • FOXP3delta7 antibody
      • Immune dysregulation polyendocrinopathy enteropathy X linked antibody
      • Immunodeficiency polyendocrinopathy enteropathy X linked antibody
      • IPEX antibody
      • JM2 antibody
      • MGC141961 antibody
      • MGC141963 antibody
      • OTTHUMP00000025832 antibody
      • OTTHUMP00000025833 antibody
      • OTTHUMP00000226737 antibody
      • PIDX antibody
      • Scurfin antibody
      • XPID antibody
      see all

    Anti-FOXP3 antibody 图像

    • All lanes : Anti-FOXP3 antibody (ab86006) at 1/1000 dilution (in 5% non-fat milk-PBST solution incubated for 60 minutes)

      Lane 1 : uninduced culture of E. coli (plus anti thio at 1/5000 dilution)
      Lane 2 : induced culture of E. coli (plus anti thio at 1/5000 dilution)

      Secondary
      anti-Rabbit IgG HRP conjugate incubated for 60 minutes at 1/1000 dilution

      Predicted band size : 47 kDa
      Observed band size : 61 kDa (why is the actual band size different from the predicted?)

    Anti-FOXP3 antibody (ab86006)参考文献

    ab86006 has not yet been referenced specifically in any publications.

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