Anti-FOXN1抗体(ab26069)
Key features and details
- Goat polyclonal to FOXN1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-FOXN1抗体
参阅全部 FOXN1 一抗 -
描述
山羊多克隆抗体to FOXN1 -
宿主
Goat -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide:
SVYLSPSSKPVALA
, corresponding to C terminal amino acids 635-648 of Human FOXN1(Peptide available as ab45510.) -
阳性对照
- IHC-P: Human thymus tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
This antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab26069于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P | (1) |
Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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说明 |
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IHC-P
Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
靶标
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功能
Transcriptional regulator involved in development. -
组织特异性
Expressed in thymus. -
疾病相关
Defects in FOXN1 are the cause of T-cell immunodeficiency congenital alopecia and nail dystrophy (TIDAND) [MIM:601705]. A disorder characterized by the association of congenital alopecia, severe T-cell immunodeficiency, and ridging and pitting of all nails. -
序列相似性
Contains 1 fork-head DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 8456 Human
- Omim: 600838 Human
- SwissProt: O15353 Human
- Unigene: 663679 Human
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别名
- FKHL20 antibody
- Forkhead box N1 antibody
- Forkhead box protein N1 antibody
see all
图片
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded human thymus tissue labeling FOXN1 with ab26069 at 4 ug/ml.
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Immunohistochemical analysis of formaldehyde-fixed paraffin-embedded human skin tissue sections, labelling FOXN1 with ab26069 at a dilution of 1/25 incubated for 18 hours at 4°C. Permeablization was with 0.05% Tween. Blocking was with 5% serum incubated for 20 minutes at room temperature. The secondary used was a swine polyclonal biotin-conjugate at 1/1000.
数据表及文件
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Datasheet download
文献 (2)
ab26069 被引用在 2 文献中.
- Suzuki S et al. Transcriptional and histological analyses of the thymic developmental process in the fetal pig. Exp Anim 63:215-25 (2014). IHC ; Pig . PubMed: 24770647
- Weissferdt A & Moran CA Thymic carcinoma, part 1: a clinicopathologic and immunohistochemical study of 65 cases. Am J Clin Pathol 138:103-14 (2012). IHC-P ; Human . PubMed: 22706865