Anti-FOXI1抗体(ab20454)
Key features and details
- Goat polyclonal to FOXI1
- Suitable for: WB, IHC-P, ChIP, IHC-Fr
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-FOXI1抗体
参阅全部 FOXI1 一抗 -
描述
山羊多克隆抗体to FOXI1 -
宿主
Goat -
特异性
This antibody is expected to recognise both reported human isoforms.
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经测试应用
适用于: WB, IHC-P, ChIP, IHC-Frmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide within Human FOXI1 aa 350 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q12951 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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ChIP Related Products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab20454于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 41 kDa.
Primary incubation 1 hour at room temperature. |
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IHC-P | (1) |
Use at an assay dependent concentration. PubMed: 21303954
|
ChIP |
Use at an assay dependent concentration. PubMed: 20972246
|
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IHC-Fr |
Use at an assay dependent concentration. PubMed: 16932748
An antigen retrieval method using SDS is described in PubMed 16932748 and PubMed 9072183. |
说明 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 41 kDa. Primary incubation 1 hour at room temperature. |
IHC-P
Use at an assay dependent concentration. PubMed: 21303954 |
ChIP
Use at an assay dependent concentration. PubMed: 20972246 |
IHC-Fr
Use at an assay dependent concentration. PubMed: 16932748 An antigen retrieval method using SDS is described in PubMed 16932748 and PubMed 9072183. |
靶标
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功能
Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules. -
组织特异性
Expressed in kidney. -
序列相似性
Contains 1 fork-head DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 2299 Human
- Omim: 601093 Human
- SwissProt: Q12951 Human
- Unigene: 87236 Human
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别名
- FKH10 antibody
- FKHL10 antibody
- Forkhead (Drosophila) like 10 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (11)
ab20454 被引用在 11 文献中.
- Xue X et al. Tumour cells are sensitised to ferroptosis via RB1CC1-mediated transcriptional reprogramming. Clin Transl Med 12:e747 (2022). PubMed: 35220675
- Montoro DT et al. A revised airway epithelial hierarchy includes CFTR-expressing ionocytes. Nature 560:319-324 (2018). PubMed: 30069044
- Plasschaert LW et al. A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte. Nature 560:377-381 (2018). PubMed: 30069046
- Honda K et al. Molecular architecture underlying fluid absorption by the developing inner ear. Elife 6:N/A (2017). IHC ; Mouse . PubMed: 28994389
- Björkgren I et al. Targeted inactivation of the mouse epididymal beta-defensin 41 alters sperm flagellar beat pattern and zona pellucida binding. Mol Cell Endocrinol 427:143-54 (2016). PubMed: 26987518