Anti-Folate Binding Protein抗体(HRP) - Azide free (ab20572)


  • 产品名称Anti-Folate Binding Protein抗体(HRP) - Azide free
    参阅全部 Folate Binding Protein 一抗
  • 描述
    山羊多克隆抗体to Folate Binding Protein - Azide free (HRP)
  • 偶联物HRP
  • 特异性This antibody targets both purified and partially purified Folate Binding Protein from bovine milk.
  • 经测试应用适用于: WB, Dot Blot, ELISA, IHC-P, IHC-Fr, Immunomicroscopymore details
  • 种属反应性
    与反应: Cow
  • 免疫原

    Folate Binding Protein (bovine milk).


  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.01% Gentamicin Sulfate
    Constituents: PBS, 10mg/ml Polyethylene glycol (PEG 8000). pH 7.2
  • Concentration information loading...
  • 纯化说明Purified from monospecific antiserum by delipidation, fractionation and ion exchange chromatography.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域


Our Abpromise guarantee covers the use of ab20572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 31 kDa.
Dot Blot Use at an assay dependent dilution.
ELISA 1/2000 - 1/12000.
IHC-P 1/100 - 1/200.
IHC-Fr 1/100 - 1/200.
Immunomicroscopy Use at an assay dependent dilution.


  • 功能Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
  • 组织特异性Exclusively expressed in tissues of epithelial origin. Expression is increased in malignant tissues. Expressed in kidney, lung and cerebellum.
  • 疾病相关Defects in FOLR1 are the cause of neurodegeneration due to cerebral folate transport deficiency (NCFTD) [MIM:613068]. NCFTD is an autosomal recessive disorder resulting from brain-specific folate deficiency early in life. Onset is apparent in late infancy with severe developmental regression, movement disturbances, epilepsy, and leukodystrophy. Note=Recognition and diagnosis of this disorder is critical because folinic acid therapy can reverse the clinical symptoms and improve brain abnormalities and function.
  • 序列相似性Belongs to the folate receptor family.
  • 翻译后修饰Eight disulfide bonds are present.
    The secreted form is derived from the membrane-bound form either by cleavage of the GPI anchor, or/and by proteolysis catalyzed by a metalloprotease.
  • 细胞定位Cell membrane. Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • adult antibody
    • Adult folate binding protein antibody
    • Adult folate-binding protein antibody
    • FBP antibody
    • Folate Receptor 1 Adult antibody
    • Folate receptor 1 antibody
    • Folate Receptor 1 Precursor antibody
    • Folate receptor adult antibody
    • Folate receptor alpha antibody
    • Folate receptor antibody
    • FOLR antibody
    • FOLR1 antibody
    • FOLR1_HUMAN antibody
    • FR alpha antibody
    • FR-alpha antibody
    • FRalpha antibody
    • KB cells FBP antibody
    • MOV18 antibody
    • Ovarian cancer associated antigen antibody
    • Ovarian tumor associated antigen antibody
    • Ovarian tumor associated antigen MOv18 antibody
    • Ovarian tumor-associated antigen MOv18 antibody
    see all

Anti-Folate Binding Protein antibody (HRP) - Azide free 图像

  • Immunohistochemical analysis of Human clear cell ovarian carcinoma tissue, staining Folate Binding Protein with ab20572 at 1/200 dilution.

Anti-Folate Binding Protein antibody (HRP) - Azide free (ab20572)参考文献

This product has been referenced in:
  • Siu MK  et al. Paradoxical impact of two folate receptors, FRa and RFC, in ovarian cancer: effect on cell proliferation, invasion and clinical outcome. PLoS One 7:e47201 (2012). IHC-P . Read more (PubMed: 23144806) »

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