Anti-Focadhesin抗体(ab185462)

概述

  • 产品名称
    Anti-Focadhesin抗体
  • 描述
    兔多克隆抗体to Focadhesin
  • 宿主
    Rabbit
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment corresponding to Human Focadhesin aa 1407-1533.
    Sequence:

    NWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNAAALLGLWVTPPLIH SLSLNTKRYLLISAPLWIKHISDEQILGFVENLMVAVFKAASPLGSPELC PSALHGLSQAMKLPSPAHHLWSLLSEA


    Database link: Q5VW36

  • 阳性对照
    • Human small intestine tissue

性能

应用

Our Abpromise guarantee covers the use of ab185462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    Potential tumor suppressor in gliomas.
  • 组织特异性
    Ubiquitous. High expression in brain followed by testis, muscle, pancreas, heart, ovary, small intestine, placenta, prostate, thymus, kidney, colon, liver, lung, spleen and leukocytes. Expression is reduced in most glioblastomas and all glioblastoma cell lines.
  • 细胞定位
    Membrane. Cell junction > focal adhesion. Colocalizes with VCL in astrocytes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FOCAD antibody
    • FOCAD_HUMAN antibody
    • Focadhesin antibody
    • KIAA1797 antibody

图片

  • Immunohistochemical analysis of paraffin-embedded Human small intestine tissue labeling Focadhesin with ab185462 at 1/50 dilution.

文献

ab185462 has not yet been referenced specifically in any publications.

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