概述

  • 产品名称Anti-FNTA抗体[EPR4704]
    参阅全部 FNTA 一抗
  • 描述
    兔单克隆抗体[EPR4704] to FNTA
  • 经测试应用适用于: WB, IHC-P, Flow Cytmore details
    不适用于: ICC or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human FNTA.

  • 阳性对照
    • Jurkat, HeLa, JAR, C6, RAW264.7, PC12, and NIH3T3 cell lysates.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

应用

Our Abpromise guarantee covers the use of ab109738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 44 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol. Antigen retrieval recommended; heat up to 98 degrees C, below boiling, and then let cool for 10-20 min.
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 应用说明Is unsuitable for ICC or IP.
  • 靶标

    • 功能Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK.
    • 序列相似性Belongs to the protein prenyltransferase subunit alpha family.
      Contains 5 PFTA repeats.
    • 翻译后修饰Phosphorylated. Phosphorylation is mediated by MUSK upon AGRIN stimulation and results in the activation of FNTA.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CAAX farnesyltransferase alpha subunit antibody
      • CAAX farnesyltransferase subunit alpha antibody
      • EC 2.5.1.58 antibody
      • EC 2.5.1.59 antibody
      • Farnesyl protein transferase alpha subunit antibody
      • Farnesyltransferase CAAX box alpha antibody
      • Farnesyltransferase, CAAX box, alpha antibody
      • Fnta antibody
      • FNTA_HUMAN antibody
      • FPTA antibody
      • FTase alpha antibody
      • FTase-alpha antibody
      • GGTase I alpha antibody
      • GGTase-I-alpha antibody
      • MGC99680 antibody
      • OTTHUMP00000229206 antibody
      • OTTHUMP00000229262 antibody
      • PGGT1A antibody
      • Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit antibody
      • Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha antibody
      • Protein prenyltransferase alpha subunit repeat containing 2 antibody
      • PTAR2 antibody
      • Ras proteins prenyltransferase alpha antibody
      • Ras proteins prenyltransferase subunit alpha antibody
      • Type I protein geranyl geranyltransferase alpha subunit antibody
      • Type I protein geranyl-geranyltransferase subunit alpha antibody
      see all

    Anti-FNTA antibody [EPR4704] 图像

    • All lanes : Anti-FNTA antibody [EPR4704] (ab109738) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : JAR cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 44 kDa
    • All lanes : Anti-FNTA antibody [EPR4704] (ab109738) at 1/1000 dilution

      Lane 1 : C6 cell lysate
      Lane 2 : RAW264.7 cell lysate
      Lane 3 : PC12 cell lysate
      Lane 4 : NIH3T3 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 44 kDa

    Anti-FNTA antibody [EPR4704] (ab109738)参考文献

    This product has been referenced in:
    • Miles RR  et al. Genome-wide screen for modulation of hepatic apolipoprotein A-I (ApoA-I) secretion. J Biol Chem 288:6386-96 (2013). WB ; Human . Read more (PubMed: 23322769) »

    See 1 Publication for this product

    Product Wall

    Thank you for contacting Abcam. The antibody ab109738 maps to between amino acids********* of human FNTA (UniProt: P49354). Please let me know if you have any other questions.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"