概述

  • 产品名称Anti-FNIP2抗体
    参阅全部 FNIP2 一抗
  • 描述
    兔多克隆抗体to FNIP2
  • 特异性Multiple isoforms of FNIP2 are known to exist. This antibody is predicted not to cross-react with FNIP1.
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    An 18 amino acid peptide near the N terminus of Human FNIP2 (NP_065891).

  • 阳性对照
    • Mouse skeletal muscle lysate

性能

应用

Our Abpromise guarantee covers the use of ab106605 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 122 kDa.

靶标

  • 功能May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity). May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.
  • 组织特异性Widely expressed with highest levels in muscle, nasal mucosa, salivary gland, uvula, fat, liver, heart, placenty and pancreas. Moderately expressed in the lung, small intestine, kidney and brain. Lower levels detected in renal cell carcinoma than in normal kidney tissue. Higher levels detected in oncocytoma than in normal kidney.
  • 序列相似性Belongs to the FNIP family.
  • 翻译后修饰Phosphorylated by AMPK.
  • 细胞定位Cytoplasm. Co-localizes with FLCN in the cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FNIP1-like protein antibody
    • Fnip2 antibody
    • FNIP2_HUMAN antibody
    • FNIPL antibody
    • Folliculin-interacting protein 2 antibody
    • KIAA1450 antibody
    • MAPO1 antibody
    • O6-methylguanine-induced apoptosis 1 protein antibody
    • OTTHUMP00000221326 antibody
    see all

Anti-FNIP2 antibody 图像

  • Lane 1 : Anti-FNIP2 antibody (ab106605) at 1 µg/ml
    Lane 2 : Anti-FNIP2 antibody (ab106605) at 2 µg/ml

    Lane 1 : Mouse skeletal muscle lysate
    Lane 2 : Mouse skeletal muscle lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 122 kDa

Anti-FNIP2 antibody (ab106605)参考文献

ab106605 has not yet been referenced specifically in any publications.

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