这个 快线抗体 还未被充份测试和鉴定,因此它受制于相关的 使用条款

概述

  • 产品名称
  • 描述
    山羊多克隆抗体to FNBP3

    该产品是 快线抗体,通过亲和纯化得到。对抗原肽有高灵敏度及特异性(ELISA测试)。 Read the terms of use »

  • 种属反应性

    预测可用于: Mouse, Rat, Dog, Human, Pig
  • 免疫原

    Synthetic peptide: KRRRTLLEQLDDDQ, corresponding to C terminal amino acids 944-957 of Human FNBP3.

  • 常规说明
    GenBank Accession Number - AAH27178; XP_371575

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris-saline. pH 7.3
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 110 kDa.Can be blocked with Human FNBP3 peptide (ab23236). Preliminary experiments gave an ~28kDa band in A549 lysates at 1ug/ml, this band was successfully blocked by incubation with the immunising peptide. Please note that currently we cannot find a definitive explanation in the literature for the band we observe given the predicted size of ~110kDda.

靶标

  • 功能
    Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). May be involved in pre-mRNA splicing.
  • 组织特异性
    Expressed in the brain cortex (at protein level). Widely expressed.
  • 序列相似性
    Belongs to the PRPF40 family.
    Contains 5 FF domains.
    Contains 2 WW domains.
  • 结构域
    The WW domains are essential for localization to nuclear speckles.
  • 细胞定位
    Nucleus speckle. Nucleus matrix. Colocalizes with AKAP8L in the nuclear matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Fas ligand associated factor 1 antibody
    • Fas ligand-associated factor 1 antibody
    • FBP 11 antibody
    • FBP11 antibody
    • FLAF 1 antibody
    • FLAF1 antibody
    • FNBP 3 antibody
    • Formin binding protein 11 antibody
    • Formin binding protein 3 antibody
    • Formin-binding protein 11 antibody
    • Formin-binding protein 3 antibody
    • HIP-10 antibody
    • HIP10 antibody
    • Huntingtin interacting protein A antibody
    • Huntingtin interacting protein HYPA antibody
    • Huntingtin yeast partner A antibody
    • Huntingtin-interacting protein 10 antibody
    • Huntingtin-interacting protein A antibody
    • HYPA antibody
    • NY REN 6 antibody
    • NY REN 6 antigen antibody
    • PR40A_HUMAN antibody
    • Pre mRNA processing factor 40 homolog A antibody
    • Pre-mRNA-processing factor 40 homolog A antibody
    • PRP40 pre mRNA processing factor 40 homolog A (S cerevisiae) antibody
    • PRP40 pre mRNA processing factor 40 homolog A (yeast) antibody
    • PRP40 pre mRNA processing factor 40 homolog A antibody
    • PRPF 40A antibody
    • PRPF40A antibody
    • Renal carcinoma antigen NY-REN-6 antibody
    see all

实验方案

文献

ab13774 has not yet been referenced specifically in any publications.

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