概述

  • 产品名称Anti-FNBP1L抗体
    参阅全部 FNBP1L 一抗
  • 描述
    兔多克隆抗体to FNBP1L
  • 经测试应用适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Platypus (Ornithorhynchus anatinus), Elephant
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 50-100 of Human FNBP1L (NP_001157945.1).

  • 阳性对照
    • Jurkat whole cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab124277 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at 2-10 µg/mg of lysate.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles.
    • 序列相似性Belongs to the FNBP1 family.
      Contains 1 FCH domain.
      Contains 1 REM (Hr1) repeat.
      Contains 1 SH3 domain.
    • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton. Cytoplasm > cell cortex. Cytoplasmic vesicle. Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • C1orf39 antibody
      • FBP1L_HUMAN antibody
      • FNBP 1L antibody
      • fnbp1l antibody
      • Formin binding protein 1 like antibody
      • Formin-binding protein 1-like antibody
      • TOCA 1 antibody
      • Toca-1 antibody
      • TOCA1 antibody
      • Transducer of Cdc42 dependent actin assembly 1 antibody
      • Transducer of Cdc42 dependent actin assembly protein 1 antibody
      • Transducer of Cdc42-dependent actin assembly protein 1 antibody
      see all

    Anti-FNBP1L antibody 图像

    • Lane 1: Staining of FNBP1L in Jurkat whole cell lysate immunoprecipitated using ab124277 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2: control IgG.
      Predicted band size : 70 kDa. Exposure time: 30 seconds

    Anti-FNBP1L antibody (ab124277)参考文献

    ab124277 has not yet been referenced specifically in any publications.

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