概述

  • 产品名称Anti-FMO3抗体
    参阅全部 FMO3 一抗
  • 描述
    小鼠多克隆抗体to FMO3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human FMO3 protein (AAH32016.1)

  • 阳性对照
    • Human liver tissue lysate, FMO3 transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab92902 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/500 - 1/1000. Predicted molecular weight: 60 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. Plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds.
    • 组织特异性Liver.
    • 疾病相关Defects in FMO3 are the cause of trimethylaminuria (TMAU) [MIM:602079]; also known as fish-odor syndrome. TMAU is an inborn error of metabolism associated with an offensive body odor and caused by deficiency of FMO-mediated N-oxidation of amino-trimethylamine (TMA) derived from foodstuffs. Such individuals excrete relatively large amounts of TMA in their urine, sweat, and breath, and exhibit a fishy body odor characteristic of the malodorous free amine.
    • 序列相似性Belongs to the FMO family.
    • 细胞定位Microsome membrane. Endoplasmic reticulum membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Dimethylaniline monooxygenase [N oxide forming] 3 antibody
      • Dimethylaniline monooxygenase [N-oxide-forming] 3 antibody
      • Dimethylaniline monooxygenase 3 antibody
      • Dimethylaniline oxidase 3 antibody
      • dJ127D3.1 antibody
      • Flavin containing monooxygenase 3 antibody
      • FMO 3 antibody
      • FMO form 2 antibody
      • FMO II antibody
      • FMO3 antibody
      • FMO3_HUMAN antibody
      • FMOII antibody
      • Hepatic flavin containing monooxygenase 3 antibody
      • Hepatic flavin-containing monooxygenase 3 antibody
      • MGC34400 antibody
      • TMAU antibody
      • Trimethylamine monooxygenase antibody
      see all

    Anti-FMO3 antibody 图像

    • Anti-FMO3 antibody (ab92902) at 1/500 dilution + Human liver tissue lysate at 50 µg

      Predicted band size : 60 kDa
    • All lanes : Anti-FMO3 antibody (ab92902) at 1/500 dilution

      Lane 1 : FMO3 transfected 293T cell lysate
      Lane 2 : Untransfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.


      Predicted band size : 60 kDa
      Observed band size : 59 kDa (why is the actual band size different from the predicted?)

    Anti-FMO3 antibody (ab92902)参考文献

    ab92902 has not yet been referenced specifically in any publications.

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