Anti-FMNL2抗体[2B4] (ab57963)
Key features and details
- Mouse monoclonal [2B4] to FMNL2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-FMNL2抗体[2B4]
参阅全部 FMNL2 一抗 -
描述
小鼠单克隆抗体[2B4] to FMNL2 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein, corresponding to amino acids 1-179 of Human FMNL2
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常规说明
This product was changed from ascites to tissue culture supernatant on 17/04/2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.4 -
Concentration information loading...
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纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
2B4 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab57963于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 124 kDa.
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说明 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 124 kDa. |
靶标
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相关性
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined. -
细胞定位
Cytoplasm -
数据库链接
- Entrez Gene: 114793 Human
- Omim: 616285 Human
- SwissProt: Q96PY5 Human
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别名
- FHOD2 antibody
- Formin homology 2 domain containing protein 2 antibody
- Formin like 2 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (10)
ab57963 被引用在 10 文献中.
- Kage F et al. Lamellipodia-like actin networks in cells lacking WAVE regulatory complex. J Cell Sci 135:N/A (2022). PubMed: 35971979
- Katsuno-Kambe H et al. Caveolin-1 influences epithelial collective cell migration via FMNL2 formin. Biol Cell 113:107-117 (2021). PubMed: 33169848
- Dimchev V et al. Induced Arp2/3 Complex Depletion Increases FMNL2/3 Formin Expression and Filopodia Formation. Front Cell Dev Biol 9:634708 (2021). PubMed: 33598464
- Ivanov SS et al. Neisseria gonorrhoeae subverts formin-dependent actin polymerization to colonize human macrophages. PLoS Pathog 17:e1010184 (2021). PubMed: 34962968
- Li Y et al. Inhibition of formin like 2 promotes the transition of ectopic endometrial stromal cells to epithelial cells in adenomyosis through a MET-like process. Gene 710:186-192 (2019). PubMed: 31175924
- Jones MC et al. Cell adhesion is regulated by CDK1 during the cell cycle. J Cell Biol 217:3203-3218 (2018). PubMed: 29930204
- Kage F et al. FMNL formins boost lamellipodial force generation. Nat Commun 8:14832 (2017). PubMed: 28327544
- Kage F et al. FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42. Sci Rep 7:9791 (2017). PubMed: 28852060
- Gardberg M et al. Characterization of Leukocyte Formin FMNL1 Expression in Human Tissues. J Histochem Cytochem 62:460-470 (2014). PubMed: 24700756
- Chazeau A et al. Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion. EMBO J 33:2745-64 (2014). PubMed: 25293574