Anti-FMNL1抗体[2369E4a] (ab54361)


  • 产品名称Anti-FMNL1抗体[2369E4a]
    参阅全部 FMNL1 一抗
  • 描述
    小鼠单克隆抗体[2369E4a] to FMNL1
  • 经测试应用适用于: WB, Dot Blotmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    FMNL1 recombinant fragment (Human)


  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明ab54361 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane.
  • 克隆单克隆
  • 克隆编号2369E4a
  • 同种型IgG1
  • 研究领域


Our Abpromise guarantee covers the use of ab54361 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 122 kDa.
Dot Blot Use at an assay dependent dilution.


  • 功能May play a role in the control of cell motility and survival of macrophages (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape.
  • 组织特异性Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • 序列相似性Belongs to the formin homology family.
    Contains 1 DAD (diaphanous autoregulatory) domain.
    Contains 1 FH2 (formin homology 2) domain.
    Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain.
  • 结构域The DAD domain regulates activation via by an autoinhibitory interaction with the N-terminus. This autoinhibition is released upon competitive binding of an activated GTPase. The release of DAD allows the FH2 domain to then nucleate and elongate nonbranched actin filaments.
  • 翻译后修饰Myristoylation mediates membrane localization and blebbing.
  • 细胞定位Cytoplasm > cell cortex. Cell projection > bleb. Colocalized with F-actin in bleb protrusions and Cytoplasm. Cell membrane. Cytoplasmic vesicle > phagosome. Recruited to actin-rich phagosomes during phagocytosis. Translocates to the plasma membrane upon activation by RAC1.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 8030453N10Rik antibody
    • AI553564 antibody
    • C17orf1 antibody
    • C17orf1B antibody
    • CLL associated antigen KW 13 antibody
    • CLL-associated antigen KW-13 antibody
    • FHOD4 antibody
    • FMNL antibody
    • FMNL_HUMAN antibody
    • Fmnl1 antibody
    • Fnrl antibody
    • Formin like 1 antibody
    • Formin like antibody
    • Formin related protein antibody
    • Formin-like protein 1 antibody
    • Frls antibody
    • KW 13 antibody
    • KW13 antibody
    • Leukocyte formin antibody
    • MGC133052 antibody
    • MGC1894 antibody
    • MGC21878 antibody
    see all

Anti-FMNL1 antibody [2369E4a] 图像

Anti-FMNL1 antibody [2369E4a] (ab54361)参考文献

ab54361 has not yet been referenced specifically in any publications.

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