The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 47 kDa.
Use a concentration of 3.75 µg/ml.
Use at an assay dependent concentration.
功能May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
组织特异性In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes.
序列相似性Belongs to the band 7/mec-2 family. Flotillin subfamily.
细胞定位Cell membrane. Membrane > caveola. Endosome. Membrane-associated protein of caveolae.