The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 20 µg/ml.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 47 kDa.
功能Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution.
组织特异性Widely expressed. Expressed at lower level in liver and kidney.
序列相似性Belongs to the RILPL family. Contains 1 RILP-like domain.
翻译后修饰S-nitrosylation is required for the interaction with GAPDH.