概述

  • 产品名称
    Anti-FLJ39378抗体
    参阅全部 FLJ39378 一抗
  • 描述
    兔多克隆抗体to FLJ39378
  • 经测试应用
    适用于: ICC/IF, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    17 amino acid synthetic peptide derived from near the N terminal of Human FLJ39378 (AAH89444).

  • 阳性对照
    • Rat cerebellum tissue lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab117441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 47 kDa.

靶标

  • 功能
    Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution.
  • 组织特异性
    Widely expressed. Expressed at lower level in liver and kidney.
  • 序列相似性
    Belongs to the RILPL family.
    Contains 1 RILP-like domain.
  • 翻译后修饰
    S-nitrosylation is required for the interaction with GAPDH.
  • 细胞定位
    Cytoplasm > cytosol.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GOSPEL antibody
    • MGC105128 antibody
    • MGC99793 antibody
    • Rab interacting lysosomal protein like 1 antibody
    • Rab-interacting lysosomal-like protein 1 antibody
    • RILP like protein 1 antibody
    • RILP-like protein 1 antibody
    • RILPL 1 antibody
    • rilpl1 antibody
    • RIPL1_HUMAN antibody
    • RLP1 antibody
    see all

图片

  • Lane 1 : Anti-FLJ39378 antibody (ab117441) at 0.5 µg/ml
    Lane 2 : Anti-FLJ39378 antibody (ab117441) at 1 µg/ml

    Lane 1 : Rat cerebellum tissue lysate
    Lane 2 : Rat cerebellum tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 47 kDa
  • Immunofluorescence analysis of mouse brain cells, staining FLJ39378 with ab117441 at 20 µg/ml.

文献

ab117441 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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