概述

  • 产品名称Anti-FLJ39378抗体
    参阅全部 FLJ39378 一抗
  • 描述
    兔多克隆抗体to FLJ39378
  • 经测试应用适用于: ICC/IF, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    17 amino acid synthetic peptide derived from near the N terminal of Human FLJ39378 (AAH89444).

  • 阳性对照
    • Rat cerebellum tissue lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab117441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 47 kDa.

靶标

  • 功能Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution.
  • 组织特异性Widely expressed. Expressed at lower level in liver and kidney.
  • 序列相似性Belongs to the RILPL family.
    Contains 1 RILP-like domain.
  • 翻译后修饰S-nitrosylation is required for the interaction with GAPDH.
  • 细胞定位Cytoplasm > cytosol.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GOSPEL antibody
    • MGC105128 antibody
    • MGC99793 antibody
    • Rab interacting lysosomal protein like 1 antibody
    • Rab-interacting lysosomal-like protein 1 antibody
    • RILP like protein 1 antibody
    • RILP-like protein 1 antibody
    • RILPL 1 antibody
    • rilpl1 antibody
    • RIPL1_HUMAN antibody
    • RLP1 antibody
    see all

Anti-FLJ39378 antibody 图像

  • Lane 1 : Anti-FLJ39378 antibody (ab117441) at 0.5 µg/ml
    Lane 2 : Anti-FLJ39378 antibody (ab117441) at 1 µg/ml

    Lane 1 : Rat cerebellum tissue lysate
    Lane 2 : Rat cerebellum tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 47 kDa
  • Immunofluorescence analysis of mouse brain cells, staining FLJ39378 with ab117441 at 20 µg/ml.

Anti-FLJ39378 antibody (ab117441)参考文献

ab117441 has not yet been referenced specifically in any publications.

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