概述

  • 产品名称Anti-FLJ36733抗体
    参阅全部 FLJ36733 一抗
  • 描述
    兔多克隆抗体to FLJ36733
  • 经测试应用适用于: IHC-P, ICC/IF, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    antigen sequence: FKFICDASSL HQVRKKLDSL GLCSVSCALE FIPNSKVQLA EPDLEQAAHL IQALSNHEDV IHVYDNI, corresponding to C terminal amino acids 230-296 of Human FLJ36733.

  • 阳性对照
    • Human kidney tissue; U 2 OS cells; RT 4 and U 251 MG lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab121688 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100
WB 1/250 - 1/500.

靶标

  • 功能Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1.
  • 疾病相关Defects in TACO1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency.
  • 序列相似性Belongs to the TACO1 family.
  • 细胞定位Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CCDC44 antibody
    • CDNA FLJ36733 fis antibody
    • Coiled coil domain containing 44 antibody
    • Coiled-coil domain-containing protein 44 antibody
    • PRO0477 antibody
    • Taco1 antibody
    • TACO1_HUMAN antibody
    • Translational activator of cytochrome c oxidase 1 antibody
    • Translational activator of mitochondrially-encoded cytochrome c oxidase I antibody
    • UTERU2012856 antibody
    see all

Anti-FLJ36733 antibody 图像

  • Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)
    Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)
  • All lanes : Anti-FLJ36733 antibody (ab121688) at 1/250 dilution

    Lane 1 : RT 4 lysate
    Lane 2 : U 251 MG lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human tonsil lysate

    Developed using the ECL technique
  • ab121688 at 1/75 dilution staining FLJ36733 in Paraffin-embedded Human kidney tissue by Immunohistochemistry.
  • ab121688 at 4 µg/ml staining FLJ36733 in PFA/Triton X-100 fixed/permeabilized U 2 OS cells by Immunofluorescence (green).

Anti-FLJ36733 antibody (ab121688)参考文献

This product has been referenced in:
  • Lee DE  et al. Translational machinery of mitochondrial mRNA is promoted by physical activity in Western diet-induced obese mice. Acta Physiol (Oxf) 218:167-177 (2016). Read more (PubMed: 27061106) »

See 1 Publication for this product

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