RabMAb

Anti-FKBP6抗体[EPR3674] (ab92475)

概述

  • 产品名称Anti-FKBP6抗体[EPR3674]
    参阅全部 FKBP6 一抗
  • 描述
    兔单克隆抗体[EPR3674] to FKBP6
  • 经测试应用适用于: WB, IHC-P, Flow Cytmore details
    不适用于: ICC/IF or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to residues near the C terminus in Human FKBP6

  • 阳性对照
    • Molt-4 and SAOS-2 cell lysates. Human tonsil tissue.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 纯度Tissue culture supernatant
  • 克隆单克隆
  • 克隆编号EPR3674
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab92475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
Flow Cyt
  • 应用说明Flow Cyt: 1/10 - 1/100.
    IHC-P: 1/100 - 1/250 antigen retrieval is recommended.
    WB: 1/1000 - 1/10000. Detects a band of approximately 38 kDa (predicted molecular weight: 37 kDa).

    Is unsuitable for ICC/IF or IP.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能PPIases accelerate the folding of proteins.
    • 组织特异性Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.
    • 疾病相关Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
    • 序列相似性Contains 1 PPIase FKBP-type domain.
      Contains 3 TPR repeats.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 36 kDa FK506 binding protein antibody
      • 36 kDa FK506-binding protein antibody
      • 36 kDa FKBP antibody
      • EC 5.2.1.8 antibody
      • FK506 binding protein 6 antibody
      • FK506-binding protein 6 antibody
      • FKBP 36 antibody
      • FKBP-36 antibody
      • FKBP-6 antibody
      • FKBP36 antibody
      • fkbp6 antibody
      • FKBP6_HUMAN antibody
      • Immunophilin FKBP36 antibody
      • Peptidyl prolyl cis trans isomerase antibody
      • Peptidyl-prolyl cis-trans isomerase FKBP6 antibody
      • PPIase antibody
      • PPIase FKBP6 antibody
      • Rotamase antibody
      see all

    Anti-FKBP6 antibody [EPR3674] 图像

    • All lanes : Anti-FKBP6 antibody [EPR3674] (ab92475) at 1/1000 dilution

      Lane 1 : Molt-4 cell lysate
      Lane 2 : SAOS-2 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit antibody at 1/2000 dilution

      Predicted band size : 37 kDa
      Observed band size : 38 kDa (why is the actual band size different from the predicted?)
    • Ab92475 at 1/100 dilution staining FKBP6 in paraffin-embedded Human tonsil tissue, by immunohistochemistry.

    Anti-FKBP6 antibody [EPR3674] (ab92475)参考文献

    ab92475 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"