RabMAb

Anti-FKBP6抗体[EPR3673] (ab108419)

概述

  • 产品名称Anti-FKBP6抗体[EPR3673]
    参阅全部 FKBP6 一抗
  • 描述
    兔单克隆抗体[EPR3673] to FKBP6
  • 经测试应用适用于: WB, IHC-P, Flow Cytmore details
    不适用于: ICC or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) (internal sequence)

  • 阳性对照
    • Molt-4, Saos-2, 293T and Human heart lysates; Human breast tissue
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 纯度Tissue culture supernatant
  • 克隆单克隆
  • 克隆编号EPR3673
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab108419 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50000 - 1/200000. Predicted molecular weight: 38 kDa.
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Flow Cyt 1/100 - 1/500. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 应用说明Is unsuitable for ICC or IP.
  • 靶标

    • 功能PPIases accelerate the folding of proteins.
    • 组织特异性Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.
    • 疾病相关Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
    • 序列相似性Contains 1 PPIase FKBP-type domain.
      Contains 3 TPR repeats.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 36 kDa FK506 binding protein antibody
      • 36 kDa FK506-binding protein antibody
      • 36 kDa FKBP antibody
      • EC 5.2.1.8 antibody
      • FK506 binding protein 6 antibody
      • FK506-binding protein 6 antibody
      • FKBP 36 antibody
      • FKBP-36 antibody
      • FKBP-6 antibody
      • FKBP36 antibody
      • fkbp6 antibody
      • FKBP6_HUMAN antibody
      • Immunophilin FKBP36 antibody
      • Peptidyl prolyl cis trans isomerase antibody
      • Peptidyl-prolyl cis-trans isomerase FKBP6 antibody
      • PPIase antibody
      • PPIase FKBP6 antibody
      • Rotamase antibody
      see all

    Anti-FKBP6 antibody [EPR3673] 图像

    • All lanes : Anti-FKBP6 antibody [EPR3673] (ab108419) at 1/50000 dilution

      Lane 1 : Molt-4 cell lysate
      Lane 2 : Saos-2 cell lysate
      Lane 3 : 293T cell lysate
      Lane 4 : Human heart lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 38 kDa
    • ab108419, at 1/100 dilution, staining FKBP6 in paraffin-embedded Human breast tissue by Immunohistochemistry.

    Anti-FKBP6 antibody [EPR3673] (ab108419)参考文献

    ab108419 has not yet been referenced specifically in any publications.

    Product Wall


    I have issued a free of charge replacement with the order number **** for ab92475.

    To check the status of the order please contact our Customer Service team and reference this number.

    Please note that this free of charge repl...

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    Thank you for the WB details. I see nothing wrong with your protocol. Loading more sample might help but you should see something with 10ug of this lysate.

    We do not have a different lot of this antibody and I am concerned that another vial ...

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    Thank you for bringing this to our attention.

    Can you please provide a few details of your protocol? If there are no suggestions we can make, then a replacement will not be a problem.

    How are the 293T lysates prepared? Do you incl...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"