概述

  • 产品名称Anti-FKBP6抗体
    参阅全部 FKBP6 一抗
  • 描述
    兔多克隆抗体to FKBP6
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide: CAESDKFCAL SAEQQDQFPL QKVLKVAATE REFGNYLFRQ NRFYDAKVRY, corresponding to amino acids 145-194 of Human FKBP6

  • 阳性对照
    • HepG2 cell lysate Human kidney tissue

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab58694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

靶标

  • 功能PPIases accelerate the folding of proteins.
  • 组织特异性Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.
  • 疾病相关Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
  • 序列相似性Contains 1 PPIase FKBP-type domain.
    Contains 3 TPR repeats.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 36 kDa FK506 binding protein antibody
    • 36 kDa FK506-binding protein antibody
    • 36 kDa FKBP antibody
    • EC 5.2.1.8 antibody
    • FK506 binding protein 6 antibody
    • FK506-binding protein 6 antibody
    • FKBP 36 antibody
    • FKBP-36 antibody
    • FKBP-6 antibody
    • FKBP36 antibody
    • fkbp6 antibody
    • FKBP6_HUMAN antibody
    • Immunophilin FKBP36 antibody
    • Peptidyl prolyl cis trans isomerase antibody
    • Peptidyl-prolyl cis-trans isomerase FKBP6 antibody
    • PPIase antibody
    • PPIase FKBP6 antibody
    • Rotamase antibody
    see all

Anti-FKBP6 antibody 图像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling FKBP6 with ab58694 at 4-8µg/ml. Arrows indicate positively labelled epithelial cells of the renal tubule. Magnification: 400X.

  • Anti-FKBP6 antibody (ab58694) at 1.25 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 37 kDa
    Observed band size : 37 kDa
    Gel concentration: 12%

Anti-FKBP6 antibody (ab58694)参考文献

ab58694 has not yet been referenced specifically in any publications.

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