概述

  • 产品名称Anti-FKBP1B抗体
    参阅全部 FKBP1B 一抗
  • 描述
    兔多克隆抗体to FKBP1B
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide selected from the N terminal region of FKBP1B (Human) conjugated to KLH

  • 阳性对照
    • CEM cell line lysate; mouse cerebellum tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab82316 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Predicted molecular weight: 12 kDa.
ELISA 1/1000.

靶标

  • 功能Associates with the ryanodine receptor (RYR-2) in cardiac muscle sarcoplasmic reticulum and may play a unique physiological role in excitation-contraction coupling in cardiac muscle. There are four molecules of FKBP12.6 per heart muscle RYR. Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
  • 组织特异性Isoform 1 and isoform 2 are Ubiquitous with highest levels in brain and thymus.
  • 序列相似性Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
    Contains 1 PPIase FKBP-type domain.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 12.6 kDa FK506-binding protein antibody
    • 12.6 kDa FKBP antibody
    • Calstabin 2 antibody
    • FK506 binding protein 1 like antibody
    • FK506 binding protein 12.6 antibody
    • FK506 binding protein 1B 12.6 kDa antibody
    • FK506 binding protein 1B antibody
    • FK506-binding protein 1B antibody
    • FKB1B_HUMAN antibody
    • FKBP 12.6 antibody
    • FKBP 1B antibody
    • FKBP 1L antibody
    • FKBP 9 antibody
    • FKBP-12.6 antibody
    • FKBP-1B antibody
    • FKBP12.6 antibody
    • Fkbp1b antibody
    • FKBP1L antibody
    • FKBP9 antibody
    • h FKBP 12 antibody
    • h-FKBP-12 antibody
    • Immunophilin FKBP12.6 antibody
    • OTK 4 antibody
    • OTK4 antibody
    • Peptidyl prolyl cis trans isomerase 1B antibody
    • Peptidyl prolyl cis trans isomerase antibody
    • Peptidyl-prolyl cis-trans isomerase FKBP1B antibody
    • PKBP 1L antibody
    • PKBP1L antibody
    • PPIase 1B antibody
    • PPIase antibody
    • PPIase FKBP1B antibody
    • Rotamase 1B antibody
    • Rotamase antibody
    see all

Anti-FKBP1B antibody 图像

  • Anti-FKBP1B antibody (ab82316) at 1/50 dilution (purified) + mouse cerebellum tissue lysate at 35 µg

    Predicted band size : 12 kDa
    Observed band size : 12 kDa
    Additional bands at : 26 kDa,42 kDa. We are unsure as to the identity of these extra bands.
  • Anti-FKBP1B antibody (ab82316) at 1/50 dilution (purified) + CEM cell line lysate at 35 µg

    Predicted band size : 12 kDa
    Observed band size : 11 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 28 kDa. We are unsure as to the identity of these extra bands.

Anti-FKBP1B antibody (ab82316)参考文献

ab82316 has not yet been referenced specifically in any publications.

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